Sarah C Lee
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Explore the profile of Sarah C Lee including associated specialties, affiliations and a list of published articles.
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22
Citations
521
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Recent Articles
1.
Li H, Pike A, Lotsaris I, Chi G, Hansen J, Lee S, et al.
Nat Commun
. 2024 Jul;
15(1):5503.
PMID: 38951531
Proline is widely known as the only proteogenic amino acid with a secondary amine. In addition to its crucial role in protein structure, the secondary amino acid modulates neurotransmission and...
2.
Wang X, Slater A, Lee S, Harrison N, Pollock N, Bakker S, et al.
Arch Biochem Biophys
. 2024 Feb;
754:109944.
PMID: 38395124
The collagen/fibrin(ogen) receptor, glycoprotein VI (GPVI), is a platelet activating receptor and a promising anti-thrombotic drug target. However, while agonist-induced GPVI clustering on platelet membranes has been shown to be...
3.
Quesnay J, Pollock N, Nagampalli R, Lee S, Balakrishnan V, Dias S, et al.
Biology (Basel)
. 2020 Nov;
9(11).
PMID: 33227948
The molecular identity of the mitochondrial pyruvate carrier (MPC) was presented in 2012, forty years after the active transport of cytosolic pyruvate into the mitochondrial matrix was first demonstrated. An...
4.
Lee S, Collins R, Lin Y, Jamshad M, Broughton C, Harris S, et al.
Sci Rep
. 2019 Dec;
9(1):18712.
PMID: 31822696
The E. coli membrane protein ZipA, binds to the tubulin homologue FtsZ, in the early stage of cell division. We isolated ZipA in a Styrene Maleic Acid lipid particle (SMALP)...
5.
Pollock N, Rai M, Simon K, Hesketh S, Teo A, Parmar M, et al.
Biochim Biophys Acta Biomembr
. 2019 Jun;
1861(8):1437-1445.
PMID: 31150633
Most membrane proteins function through interactions with other proteins in the phospholipid bilayer, the cytosol or the extracellular milieu. Understanding the molecular basis of these interactions is key to understanding...
6.
Teo A, Lee S, Pollock N, Stroud Z, Hall S, Thakker A, et al.
Sci Rep
. 2019 Feb;
9(1):1813.
PMID: 30755655
Biological characterisation of membrane proteins lags behind that of soluble proteins. This reflects issues with the traditional use of detergents for extraction, as the surrounding lipids are generally lost, with...
7.
Simon K, Pollock N, Lee S
Biochem Soc Trans
. 2018 Nov;
46(6):1495-1504.
PMID: 30464048
The use of styrene-maleic acid (SMA) for the purification of a wide range of membrane proteins (MPs) from both prokaryotic and eukaryotic sources has begun to make an impact in...
8.
Pollock N, Lee S, Patel J, Gulamhussein A, Rothnie A
Biochim Biophys Acta Biomembr
. 2017 Sep;
1860(4):809-817.
PMID: 28865797
New technologies for the purification of stable membrane proteins have emerged in recent years, in particular methods that allow the preparation of membrane proteins with their native lipid environment. Here,...
9.
Lee S, Pollock N
Biochem Soc Trans
. 2016 Aug;
44(4):1011-8.
PMID: 27528746
The use of styrene maleic acid lipid particles (SMALPs) for the purification of membrane proteins (MPs) is a rapidly developing technology. The amphiphilic copolymer of styrene and maleic acid (SMA)...
10.
Komar J, Alvira S, Schulze R, Martin R, Lycklama A Nijeholt J, Lee S, et al.
Biochem J
. 2016 Jul;
473(19):3341-54.
PMID: 27435098
Protein secretion and membrane insertion occur through the ubiquitous Sec machinery. In this system, insertion involves the targeting of translating ribosomes via the signal recognition particle and its cognate receptor...