Sarah Billington
Overview
Explore the profile of Sarah Billington including associated specialties, affiliations and a list of published articles.
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11
Citations
202
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Recent Articles
1.
Rahman M, Jahan F, Hanif S, Yeamin A, Shoab A, Andrews J, et al.
BMJ Open
. 2025 Mar;
15(3):e090703.
PMID: 40032381
Introduction: Early life soil-transmitted helminth (STH) infection and diarrhoea are associated with growth faltering, anaemia, impaired child development and mortality. Exposure to faecally contaminated soil inside the home may be...
2.
Rahman M, Jahan F, Hanif S, Yeamin A, Shoab A, Andrews J, et al.
medRxiv
. 2024 Aug;
PMID: 39108529
Introduction: Early life soil-transmitted helminth infection and diarrhea are associated with growth faltering, anemia, impaired child development, and mortality. Exposure to fecally contaminated soil inside the home may be a...
3.
Becerik-Gerber B, Lucas G, Aryal A, Awada M, Berges M, Billington S, et al.
Sci Rep
. 2022 Dec;
12(1):22092.
PMID: 36543830
Human-Building Interaction (HBI) is a convergent field that represents the growing complexities of the dynamic interplay between human experience and intelligence within built environments. This paper provides core definitions, research...
4.
Brukner A, Billington S, Benifla M, Nguyen T, Han H, Bennett O, et al.
Mol Pharm
. 2021 May;
18(6):2263-2273.
PMID: 34008992
Our goal was to measure the absolute differential abundance of key drug transporters in human epileptogenic brain tissue and to compare them between patients and at various distances from the...
5.
Storelli F, Billington S, Kumar A, Unadkat J
Clin Pharmacol Ther
. 2020 Sep;
109(3):667-675.
PMID: 32885413
The human blood-brain barrier (BBB) transporter P-gp can efflux amyloid-β (Aβ) out of the central nervous system (CNS). Aβ is thought to be the causative agent for Alzheimer's disease (AD)....
6.
Billington S, Shoner S, Lee S, Clark-Snustad K, Pennington M, Lewis D, et al.
Clin Pharmacol Ther
. 2019 May;
106(5):1056-1066.
PMID: 31102467
Using positron emission tomography imaging, we determined the hepatic concentrations and hepatobiliary transport of [ C]rosuvastatin (RSV; i.v. injection) in the absence (n = 6) and presence (n = 4...
7.
Billington S, Salphati L, Hop C, Chu X, Evers R, Burdette D, et al.
Clin Pharmacol Ther
. 2019 Jan;
106(1):228-237.
PMID: 30673124
For in vitro to in vivo extrapolation (IVIVE) of brain distribution of drugs that are transported at the human blood-brain barrier (BBB), it is important to quantify the interindividual and...
8.
Xu M, Saxena N, Vrana M, Zhang H, Kumar V, Billington S, et al.
Anal Chem
. 2018 Sep;
90(20):11873-11882.
PMID: 30204418
Subcellular fractionation of tissue homogenate provides enriched in vitro models (e.g., microsomes, cytosol, or membranes), which are routinely used in the drug metabolism or transporter activity and protein abundance studies....
9.
Kumar V, Yin J, Billington S, Prasad B, Brown C, Wang J, et al.
Drug Metab Dispos
. 2018 Aug;
46(10):1441-1445.
PMID: 30093416
Transporter expression, determined by quantitative proteomics, together with PBPK models is a promising approach for in vitro-to-in vivo extrapolation (IVIVE) of transporter-mediated drug clearance. OCT2-expressing HEK293 and MDCKII cells were...
10.
Billington S, Ray A, Salphati L, Xiao G, Chu X, Humphreys W, et al.
Drug Metab Dispos
. 2017 Nov;
46(2):189-196.
PMID: 29138286
Protein expression of major hepatobiliary drug transporters (NTCP, OATPs, OCT1, BSEP, BCRP, MATE1, MRPs, and P-gp) in cancerous (C, = 8) and adjacent noncancerous (NC, = 33) liver tissues obtained...