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Sarah Arrowsmith

Explore the profile of Sarah Arrowsmith including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 327
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Recent Articles
11.
Arrowsmith S
Mol Biol Rep . 2021 Jan; 48(1):413-423. PMID: 33386589
Accurate quantification of quantitative PCR (qPCR) data requires a set of stable reference genes (RGs) for normalisation. Despite its importance to mechanistic studies, no evaluation of RG stability has been...
12.
Wray S, Arrowsmith S
Annu Rev Physiol . 2020 Nov; 83:331-357. PMID: 33158376
We address advances in the understanding of myometrial physiology, focusing on excitation and the effects of gestation on ion channels and their relevance to labor. This review moves through pioneering...
13.
Osaghae B, Arrowsmith S, Wray S
Reprod Sci . 2020 May; 27(8):1570-1579. PMID: 32430707
Magnesium sulfate is used as a tocolytic, but clinical efficacy has been seriously questioned. Our objective was to use controlled ex vivo conditions and known pregnancy stages, to investigate how...
14.
Arrowsmith S, Fang Y, Sharp A
PLoS One . 2020 Jan; 15(1):e0227882. PMID: 31951633
Preterm birth is recognized as the primary cause of infant mortality worldwide. Twin pregnancies are significantly more at risk of preterm birth than singleton pregnancies. A greater understanding of why...
15.
Osaghae B, Arrowsmith S, Wray S
Reprod Sci . 2019 Feb; :1933719119828089. PMID: 30773125
Magnesium sulfate is used as a tocolytic, but clinical efficacy has been seriously questioned. Our objective was to use controlled ex vivo conditions and known pregnancy stages, to investigate how...
16.
Arrowsmith S, Keov P, Muttenthaler M, Gruber C
J Vis Exp . 2018 Feb; (131). PMID: 29443077
Discovery and characterization of novel pharmaceutical compounds or biochemical probes rely on robust and physiologically relevant assay systems. We describe methods to measure ex vivo myometrium contractility. This assay can...
17.
Muttenthaler M, Andersson A, Vetter I, Menon R, Busnelli M, Ragnarsson L, et al.
Sci Signal . 2017 Dec; 10(508). PMID: 29208680
Oxytocin and vasopressin mediate various physiological functions that are important for osmoregulation, reproduction, cardiovascular function, social behavior, memory, and learning through four G protein-coupled receptors that are also implicated in...
18.
Di Giglio M, Muttenthaler M, Harpsoe K, Liutkeviciute Z, Keov P, Eder T, et al.
Sci Rep . 2017 Feb; 7:41002. PMID: 28145450
Characterisation of G protein-coupled receptors (GPCR) relies on the availability of a toolbox of ligands that selectively modulate different functional states of the receptors. To uncover such molecules, we explored...
19.
Arrowsmith S, Neilson J, Wray S
Am J Obstet Gynecol . 2016 Aug; 215(6):789.e1-789.e9. PMID: 27555315
Background: Preterm birth at <37 weeks of gestation is the most common and costly complication of pregnancy and remains the leading cause of neonatal morbidity, death, and reduced achievement in...
20.
Attah A, Hellinger R, Sonibare M, Moody J, Arrowsmith S, Wray S, et al.
J Ethnopharmacol . 2016 Jan; 179:83-91. PMID: 26721222
Ethnopharmacological Relevance: People living in the tropical rain forest of South-Western Nigeria use Rinorea dentata (P. Beauv.) Kuntze (Violaceae) in ethno-veterinary medicine to facilitate parturition. There are no evidence-based pharmacological...