Sara Wojciechowski
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Explore the profile of Sara Wojciechowski including associated specialties, affiliations and a list of published articles.
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31
Citations
1125
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Recent Articles
1.
Antila S, Chilov D, Nurmi H, Li Z, Nasi A, Gotkiewicz M, et al.
Nat Cardiovasc Res
. 2024 Aug;
3:474-491.
PMID: 39087029
Discovery of meningeal lymphatic vessels (LVs) in the dura mater, also known as dural LVs (dLVs) that depend on vascular endothelial growth factor C expression, has raised interest in their...
2.
Keuters M, Antila S, Immonen R, Plotnikova L, Wojciechowski S, Lehtonen S, et al.
Transl Stroke Res
. 2024 Jun;
PMID: 38822994
Timely relief of edema and clearance of waste products, as well as promotion of anti-inflammatory immune responses, reduce ischemic stroke pathology, and attenuate harmful long-term effects post-stroke. The discovery of...
3.
Sivonen M, Sirvio K, Wojciechowski S, Kailaanmaki A, Kaipainen S, Bailey A, et al.
Front Immunol
. 2023 Oct;
14:1227064.
PMID: 37841273
Objective: Natural killer (NK) cells are a part of the innate immune system and first-line defense against cancer. Since they possess natural mechanisms to recognize and kill tumor cells, NK...
4.
Wojciechowski S, Virenque A, Vihma M, Galbardi B, Rooney E, Keuters M, et al.
Front Immunol
. 2021 Feb;
11:559810.
PMID: 33584640
Rationale: The recently discovered meningeal lymphatic vessels (mLVs) have been proposed to be the missing link between the immune and the central nervous system. The role of mLVs in modulating...
5.
Keuters M, Keksa-Goldsteine V, Dhungana H, Huuskonen M, Pomeshchik Y, Savchenko E, et al.
Sci Rep
. 2021 Feb;
11(1):3518.
PMID: 33568697
Lipid peroxidation-initiated ferroptosis is an iron-dependent mechanism of programmed cell death taking place in neurological diseases. Here we show that a condensed benzo[b]thiazine derivative small molecule with an arylthiazine backbone...
6.
Sonninen T, Hamalainen R, Koskuvi M, Oksanen M, Shakirzyanova A, Wojciechowski S, et al.
Sci Rep
. 2020 Sep;
10(1):14474.
PMID: 32879386
In Parkinson`s disease (PD), the loss of dopaminergic (DA) neurons in the substantia nigra pars compacta is associated with Lewy bodies arising from the accumulation of alpha-synuclein protein which leads...
7.
Oksanen M, Hyotylainen I, Trontti K, Rolova T, Wojciechowski S, Koskuvi M, et al.
Glia
. 2019 Nov;
68(3):589-599.
PMID: 31670864
Alzheimer's disease (AD) is a common dementia affecting a vast number of individuals and significantly impairing quality of life. Despite extensive research in animal models and numerous promising treatment trials,...
8.
Konttinen H, Cabral-da-Silva M, Ohtonen S, Wojciechowski S, Shakirzyanova A, Caligola S, et al.
Stem Cell Reports
. 2019 Sep;
13(4):669-683.
PMID: 31522977
Here we elucidate the effect of Alzheimer disease (AD)-predisposing genetic backgrounds, APOE4, PSEN1ΔE9, and APPswe, on functionality of human microglia-like cells (iMGLs). We present a physiologically relevant high-yield protocol for...
9.
Kolosowska N, Keuters M, Wojciechowski S, Keksa-Goldsteine V, Laine M, Malm T, et al.
Neurotherapeutics
. 2019 Aug;
16(4):1304-1319.
PMID: 31372938
Neuroinflammation is strongly induced by cerebral ischemia. The early phase after the onset of ischemic stroke is characterized by acute neuronal injury, microglial activation, and subsequent infiltration of blood-derived inflammatory...
10.
Lehtonen S, Sonninen T, Wojciechowski S, Goldsteins G, Koistinaho J
Front Neurosci
. 2019 May;
13:457.
PMID: 31133790
Despite decades of research, current therapeutic interventions for Parkinson's disease (PD) are insufficient as they fail to modify disease progression by ameliorating the underlying pathology. Cellular proteostasis (protein homeostasis) is...