Sara S Nunes
Overview
Explore the profile of Sara S Nunes including associated specialties, affiliations and a list of published articles.
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Articles
45
Citations
1454
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Recent Articles
1.
Mourad O, Vohra S, Nunes S
Sci Rep
. 2025 Mar;
15(1):8265.
PMID: 40065073
Sodium-glucose cotransporter 2 inhibitors (SGLT2i), such as empagliflozin, have shown remarkable benefits in reducing cardiovascular events and mortality in patients with heart failure irrespective of diabetes. Because of the magnitude...
2.
Sun X, Wu J, Mourad O, Li R, Nunes S
Stem Cell Reports
. 2025 Jan;
20(2):102394.
PMID: 39855203
People with type 2 diabetes (T2D) are at a higher risk for myocardial infarction (MI) than age-matched healthy individuals. Here, we studied cell-based cardiac regeneration post MI in T2D rats...
3.
Khan S, Ahuja N, Taib S, Vohra S, Cleaver O, Nunes S
Arterioscler Thromb Vasc Biol
. 2024 Oct;
44(12):2596-2615.
PMID: 39445426
Background: The pancreatic vasculature displays tissue-specific physiological and functional adaptations that support rapid insulin response by β-cells. However, the digestive enzymes have made it difficult to characterize pancreatic endothelial cells...
4.
Mourad O, Mastikhina O, Khan S, Sun X, Hatkar R, Williams K, et al.
ACS Mater Au
. 2023 Dec;
3(4):360-370.
PMID: 38090129
Cardiac fibrosis is a significant contributor to heart failure and is characterized by abnormal ECM deposition and impaired contractile function. We have previously developed a model of cardiac fibrosis via...
5.
Mourad O, Yee R, Li M, Nunes S
Circ Res
. 2023 Feb;
132(4):483-497.
PMID: 36795846
Heart disease is a significant burden on global health care systems and is a leading cause of death each year. To improve our understanding of heart disease, high quality disease...
6.
Sun X, Aghazadeh Y, Nunes S
Nat Protoc
. 2022 Oct;
17(12):2721-2738.
PMID: 36224469
Despite recent advances in the differentiation of human pluripotent stem cells into multiple cell types for application in replacement therapies, tissue vascularization remains a bottleneck for regenerative medicine. Fragments of...
7.
Soon K, Li M, Wu R, Zhou A, Khosraviani N, Turner W, et al.
Biomaterials
. 2022 Aug;
288:121729.
PMID: 35999080
Brain arteriovenous malformations (AVMs) are a disorder wherein abnormal, enlarged blood vessels connect arteries directly to veins, without an intervening capillary bed. AVMs are one of the leading causes of...
8.
Pieters V, Rjaibi S, Singh K, Li N, Khan S, Nunes S, et al.
Biofabrication
. 2022 Jul;
14(4).
PMID: 35896099
Obesity prevalence has reached pandemic proportions, leaving individuals at high risk for the development of diseases such as cancer and type 2 diabetes. In obesity, to accommodate excess lipid storage,...
9.
Loai S, Sun X, Husain M, Laflamme M, Yeger H, Nunes S, et al.
Front Cardiovasc Med
. 2022 Jun;
9:886687.
PMID: 35665251
Aim: To uncover sex-related microvascular abnormalities that underlie the early presentation of reduced perfusion in leg skeletal muscle in a type II rat model of diabetic cardiomyopathy. Methods And Results:...
10.
Aghazadeh Y, Sarangi F, Poon F, Nkennor B, McGaugh E, Nunes S, et al.
Stem Cell Reports
. 2022 Apr;
17(4):964-978.
PMID: 35364010
Human pluripotent stem cell (hPSC)-derived pancreatic progenitors (PPs) can be differentiated into beta-like cells in vitro and in vivo and therefore have therapeutic potential for type 1 diabetes (T1D) treatment....