Jason W Miklas
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Explore the profile of Jason W Miklas including associated specialties, affiliations and a list of published articles.
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20
Citations
805
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Recent Articles
1.
Singh P, Reeves G, Contrepois K, Papsdorf K, Miklas J, Ellenberger M, et al.
Cell
. 2024 May;
187(13):3338-3356.e30.
PMID: 38810644
Suspended animation states allow organisms to survive extreme environments. The African turquoise killifish has evolved diapause as a form of suspended development to survive a complete drought. However, the mechanisms...
2.
Papsdorf K, Miklas J, Hosseini A, Cabruja M, Morrow C, Savini M, et al.
Nat Cell Biol
. 2023 Aug;
25(10):1547.
PMID: 37567997
No abstract available.
3.
Papsdorf K, Miklas J, Hosseini A, Cabruja M, Morrow C, Savini M, et al.
Nat Cell Biol
. 2023 May;
25(5):672-684.
PMID: 37127715
Dietary mono-unsaturated fatty acids (MUFAs) are linked to longevity in several species. But the mechanisms by which MUFAs extend lifespan remain unclear. Here we show that an organelle network involving...
4.
Booth L, Shi C, Tantilert C, Yeo R, Miklas J, Hebestreit K, et al.
Nat Aging
. 2023 Apr;
2(9):809-823.
PMID: 37118502
Interactions between the sexes negatively impact health in many species. In Caenorhabditis, males shorten the lifespan of the opposite sex-hermaphrodites or females. Here we use transcriptomic profiling and targeted screens...
5.
Miklas J, Levy S, Hofsteen P, Mex D, Clark E, Muster J, et al.
iScience
. 2022 Jan;
25(1):103574.
PMID: 34988408
Heart disease is the leading cause of death with no method to repair damaged myocardium due to the limited proliferative capacity of adult cardiomyocytes. Curiously, mouse neonates and zebrafish can...
6.
Nunes S, Feric N, Pahnke A, Miklas J, Li M, Coles J, et al.
ACS Biomater Sci Eng
. 2021 Jan;
3(9):1911-1921.
PMID: 33440549
Animal models have been instrumental in providing insight into the molecular basis of disease. While such information has been successfully applied to the study of human disease, this translation would...
7.
Miklas J, Ruohola-Baker H
J Cell Signal
. 2020 Sep;
1(3):97-101.
PMID: 32995760
Fatty acid oxidation disorders unfortunately can result in the sudden unexplained death of infants. Mitochondrial trifunctional protein (MTP) deficiency is one such disease where long-chain fatty acids cannot be fully...
8.
Miklas J, Clark E, Levy S, Detraux D, Leonard A, Beussman K, et al.
Nat Commun
. 2020 May;
11(1):2387.
PMID: 32385292
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
9.
Hussein A, Wang Y, Mathieu J, Margaretha L, Song C, Jones D, et al.
Dev Cell
. 2020 Jan;
52(2):236-250.e7.
PMID: 31991105
Regulation of embryonic diapause, dormancy that interrupts the tight connection between developmental stage and time, is still poorly understood. Here, we characterize the transcriptional and metabolite profiles of mouse diapause...
10.
Miklas J, Clark E, Levy S, Detraux D, Leonard A, Beussman K, et al.
Nat Commun
. 2019 Oct;
10(1):4671.
PMID: 31604922
Mitochondrial trifunctional protein deficiency, due to mutations in hydratase subunit A (HADHA), results in sudden infant death syndrome with no cure. To reveal the disease etiology, we generated stem cell-derived...