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Sara Meninno

Explore the profile of Sara Meninno including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 84
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Recent Articles
1.
Battaglia V, Meninno S, Lattanzi A
Chemistry . 2024 Nov; 31(4):e202403769. PMID: 39526444
Optically active mandelic acid esters represent a highly valuable class of building blocks in organic synthesis and recurrent motifs embedded in bioactive compounds and drugs. Herein, we provide an enantioselective...
2.
De Vita S, Meninno S, Capasso L, Colarusso E, Chini M, Lauro G, et al.
Bioorg Med Chem . 2023 Aug; 93:117444. PMID: 37611334
Herein, we report the development of a new series of histone deacetylase inhibitors (HDACi) containing a 2-substituted 1,5-benzothiazepine scaffold. First, a virtual combinatorial library (∼1.6 × 10 items) was built...
3.
Battaglia V, Meninno S, Pellegrini A, Mazzanti A, Lattanzi A
Org Lett . 2023 Jun; 25(27):5038-5043. PMID: 37382588
An operationally simple Knoevenagel condensation/asymmetric epoxidation/domino ring-opening esterification (DROE) approach has been disclosed to successfully access a good variety of ()- and ()-α-arylglycine esters from commercially available aldehydes, phenylsulfonyl acetonitrile,...
4.
Meninno S, Lattanzi A
J Org Chem . 2023 Feb; 88(12):7888-7892. PMID: 36808952
A one-pot Knoevenagel reaction/asymmetric epoxidation/domino ring-opening cyclization (DROC) has been developed from commercial aldehydes, (phenylsulfonyl)acetonitrile, cumyl hydroperoxide, 1,2-ethylendiamines, and 1,2-ethanol amines to provide 3-aryl/alkyl piperazin-2-ones and morpholin-2-ones in yields of...
5.
Meninno S, Lattanzi A
ACS Org Inorg Au . 2022 Aug; 2(4):289-305. PMID: 35942279
Optically pure epoxides are recognized as highly valuable products and key intermediates, useful in different areas from pharmaceutical and agrochemical industries to natural product synthesis and materials science. The predictable...
6.
Franco F, Meninno S, Overgaard J, Rossi S, Benaglia M, Lattanzi A
Org Lett . 2022 Jun; 24(24):4371-4376. PMID: 35687515
A highly enantioselective one-pot synthesis of functionalized triflones, bearing a quaternary stereocenter, has been developed, exploiting the Michael reaction of α-(trifluoromethylsulfonyl) aryl acetic acid esters with -acryloyl-1-pyrazole catalyzed by commercially...
7.
Volpe C, Meninno S, Crescenzi C, Mancinelli M, Mazzanti A, Lattanzi A
Angew Chem Int Ed Engl . 2021 Aug; 60(44):23819-23826. PMID: 34437760
An enantioselective one-pot catalytic strategy to dihydroquinoxalinones, featuring novel 1-phenylsulfonyl-1-cyano enantioenriched epoxides as masked α-halo acyl halide synthons, followed by a domino ring-opening cyclization (DROC), is documented. A popular quinine-derived...
8.
Franco F, Meninno S, Lattanzi A, Puglisi A, Benaglia M
J Org Chem . 2021 Jul; 86(20):14207-14212. PMID: 34314582
A continuous flow approach to access α-trifluoromethylthiolated esters and amides using commercially available arylacetic acids and -(trifluoromethylthio)phthalimide as the electrophilic reagent is described. The experimental protocol involves the in-flow conversion...
9.
Meninno S, Carratu M, Overgaard J, Lattanzi A
Chemistry . 2021 Jan; 27(14):4573-4577. PMID: 33464645
A novel three-step four-transformation approach to highly functionalized 5-amino-3,4-dihydro-2H-pyrrole-2-carboxylic acid esters, starting from commercially available phenylsulfonylacetonitrile, aldehydes, and N-(diphenylmethylene)glycine tert-butyl ester, was developed. The one-pot strategy delivered this class of...
10.
Franco F, Meninno S, Benaglia M, Lattanzi A
Chem Commun (Camb) . 2020 Feb; 56(20):3073-3076. PMID: 32049083
Herein we disclosed a one-pot two-step protocol for the first direct, base-catalyzed α-trifluoromethylthiolation of carboxylic acid derivatives by using readily available N-acyl pyrazoles, N-(trifluoromethylthio)phthalimide and a nucleophile such as amines,...