Sara G Manore
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Explore the profile of Sara G Manore including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
281
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Recent Articles
1.
Regua A, Aguayo N, Jalboush S, Doheny D, Manore S, Zhu D, et al.
Cancers (Basel)
. 2024 Oct;
16(19).
PMID: 39410053
In the original publication [...].
2.
Doheny D, Sirkisoon S, Carpenter R, Aguayo N, Regua A, Anguelov M, et al.
Oncogene
. 2024 Apr;
43(23):1811.
PMID: 38678124
No abstract available.
3.
Najjar M, Manore S, Regua A, Lo H
Genes (Basel)
. 2022 Nov;
13(11).
PMID: 36360302
Human epidermal growth factor receptor 2 (HER2) receptor tyrosine kinase is overexpressed in 20-30% of breast cancers and is associated with poor prognosis and worse overall patient survival. Most women...
4.
Wong G, Manore S, Doheny D, Lo H
Semin Cancer Biol
. 2022 Aug;
86(Pt 3):84-106.
PMID: 35995341
Breast cancer is the most commonly diagnosed cancer and second-leading cause of cancer deaths in women. Breast cancer stem cells (BCSCs) promote metastasis and therapeutic resistance contributing to tumor relapse....
5.
Sirkisoon S, Wong G, Aguayo N, Doheny D, Zhu D, Regua A, et al.
Cancer Lett
. 2022 May;
540:215726.
PMID: 35589002
Mechanisms underlying breast cancer brain metastasis (BCBM) are still unclear. In this study, we observed that extracellular vesicles (EVs) secreted from breast cancer cells with increased expression of tGLI1, a...
6.
Manore S, Doheny D, Wong G, Lo H
Front Oncol
. 2022 Apr;
12:866014.
PMID: 35371975
Breast cancer is the most commonly diagnosed cancer in women. Metastasis is the primary cause of mortality for breast cancer patients. Multiple mechanisms underlie breast cancer metastatic dissemination, including the...
7.
Butler K, Castro A, Dwyer T, Hardwick L, Iacino M, Manore S, et al.
Bioorg Med Chem Lett
. 2021 Aug;
50:128329.
PMID: 34418572
The sphingomyelin pathway is important in cell regulation and determining cellular fate. Inhibition of sphingosine kinase isoform 1 (SK1) within this pathway, leads to a buildup of sphingosine and ceramide,...
8.
Regua A, Aguayo N, Jalboush S, Doheny D, Manore S, Zhu D, et al.
Cancers (Basel)
. 2021 Jun;
13(10).
PMID: 34066153
JAK2-STAT3 and TrkA signaling pathways have been separately implicated in aggressive breast cancers; however, whether they are co-activated or undergo functional interaction has not been thoroughly investigated. Herein we report,...
9.
Doheny D, Manore S, Wong G, Lo H
Cells
. 2020 Sep;
9(9).
PMID: 32957513
The hedgehog (HH) signaling pathway regulates normal cell growth and differentiation. As a consequence of improper control, aberrant HH signaling results in tumorigenesis and supports aggressive phenotypes of human cancers,...
10.
Doheny D, Sirkisoon S, Carpenter R, Aguayo N, Regua A, Anguelov M, et al.
Oncogene
. 2020 Sep;
39(42):6589-6605.
PMID: 32929154
Triple-negative breast cancer (TNBC) and HER2-positive breast cancer are particularly aggressive and associated with unfavorable prognosis. TNBC lacks effective treatments. HER2-positive tumors have treatment options but often acquire resistance to...