Santiago Fontenla
Overview
Explore the profile of Santiago Fontenla including associated specialties, affiliations and a list of published articles.
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11
Citations
150
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Recent Articles
1.
Diaz Soria C, Attenborough T, Lu Z, Fontenla S, Graham J, Hall C, et al.
Sci Rep
. 2024 Mar;
14(1):5974.
PMID: 38472267
Schistosomiasis is a major Neglected Tropical Disease, caused by the infection with blood flukes in the genus Schistosoma. To complete the life cycle, the parasite undergoes asexual and sexual reproduction...
2.
Marton S, Miquel E, Acosta-Rodriguez J, Fontenla S, Libisch G, Cassina P
ASN Neuro
. 2023 Aug;
15:17590914231197527.
PMID: 37644868
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by upper and lower motor neuron (MN) degeneration. Astrocytes surrounding MNs are known to modulate ALS progression. When cocultured with...
3.
White R, Sotillo J, Ancarola M, Borup A, Boysen A, Brindley P, et al.
J Extracell Vesicles
. 2023 Jan;
12(1):e12298.
PMID: 36604533
Over the last decade, research interest in defining how extracellular vesicles (EVs) shape cross-species communication has grown rapidly. Parasitic helminths, worm species found in the phyla Nematoda and Platyhelminthes, are...
4.
Fontenla S, Langleib M, de la Torre-Escudero E, Dominguez M, Robinson M, Tort J
Front Cell Infect Microbiol
. 2022 Feb;
11:812141.
PMID: 35155272
MicroRNAs (miRNAs) are important post-transcriptional regulators of gene expression being involved in many different biological processes and play a key role in developmental timing. Additionally, recent studies have shown that...
5.
Fontenla S, Rinaldi G, Tort J
Front Cell Infect Microbiol
. 2021 Jun;
11:653695.
PMID: 34123869
Platyhelminthes comprise one of the major phyla of invertebrate animals, inhabiting a wide range of ecosystems, and one of the most successful in adapting to parasitic life. Small non-coding RNAs...
6.
Lamolle G, Fontenla S, Rijo G, Tort J, Smircich P
Front Genet
. 2019 Sep;
10:771.
PMID: 31543897
In the present work, we performed a comparative genome-wide analysis of 22 species representative of the main clades and lifestyles of the phylum Platyhelminthes. We selected a set of 700...
7.
Choi Y, Fontenla S, Fischer P, Le T, Costabile A, Blair D, et al.
Mol Biol Evol
. 2019 Sep;
37(1):84-99.
PMID: 31501870
Liver and intestinal flukes of the family Fasciolidae cause zoonotic food-borne infections that impact both agriculture and human health throughout the world. Their evolutionary history and the genetic basis underlying...
8.
Radio S, Fontenla S, Solana V, Matos Salim A, Araujo F, Ortiz P, et al.
Parasit Vectors
. 2018 Jan;
11(1):56.
PMID: 29368659
Background: Fasciola hepatica is the main agent of fasciolosis, a zoonotic disease affecting livestock worldwide, and an emerging food-borne disease in humans. Even when effective treatments are available, drugs are...
9.
Fontenla S, Rinaldi G, Smircich P, Tort J
BMC Evol Biol
. 2017 Sep;
17(1):215.
PMID: 28893179
Background: Small non-coding RNAs, including miRNAs, and gene silencing mediated by RNA interference have been described in free-living and parasitic lineages of flatworms, but only few key factors of the...
10.
McNulty S, Tort J, Rinaldi G, Fischer K, Rosa B, Smircich P, et al.
PLoS Genet
. 2017 Jan;
13(1):e1006537.
PMID: 28060841
Food borne trematodes (FBTs) are an assemblage of platyhelminth parasites transmitted through the food chain, four of which are recognized as neglected tropical diseases (NTDs). Fascioliasis stands out among the...