Sang-Kyu Park
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Explore the profile of Sang-Kyu Park including associated specialties, affiliations and a list of published articles.
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Articles
84
Citations
1471
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Recent Articles
1.
Extensive transmission and variation in a functional receptor for praziquantel resistance in endemic
Berger D, Park S, Crellen T, Vianney T, Kabatereine N, Cotton J, et al.
bioRxiv
. 2024 Sep;
PMID: 39257780
Mass-drug administration (MDA) of human populations using praziquantel monotherapy has become the primary strategy for controlling and potentially eliminating the major neglected tropical disease schistosomiasis. To understand how long-term MDA...
2.
Kriska T, Natarajan J, Herrnreiter A, Park S, Pfister S, Thomas M, et al.
Am J Physiol Cell Physiol
. 2024 May;
327(1):C151-C167.
PMID: 38798270
Substance P (SP) is released from sensory nerves in the arteries and heart. It activates neurokinin-1 receptors (NK1Rs) causing vasodilation, immune modulation, and adverse cardiac remodeling. The hypothesis was tested:...
3.
Sprague D, Park S, Gramberg S, Bauer L, Rohr C, Chulkov E, et al.
Nat Struct Mol Biol
. 2024 May;
31(9):1386-1393.
PMID: 38714890
Diseases caused by parasitic flatworms impart a considerable healthcare burden worldwide. Many of these diseases-for example, the parasitic blood fluke infection schistosomiasis-are treated with the drug praziquantel (PZQ). However, PZQ...
4.
Kim S, Yoon H, Park S
Antioxidants (Basel)
. 2024 Feb;
13(2).
PMID: 38397753
Butein is a flavonoid found in many plants, including dahlia, butea, and coreopsis, and has both antioxidant and sirtuin-activating activities. In light of the postulated role of free radicals in...
5.
Park S, Sprague D, Rohr C, Chulkov E, Petrow I, Kumar S, et al.
J Biol Chem
. 2023 Dec;
300(1):105528.
PMID: 38043794
Parasitic flatworms cause various clinical and veterinary infections that impart a huge burden worldwide. The most clinically impactful infection is schistosomiasis, a neglected tropical disease caused by parasitic blood flukes....
6.
Sprague D, Kaethner M, Park S, Rohr C, Harris J, Maillard D, et al.
ACS Med Chem Lett
. 2023 Nov;
14(11):1537-1543.
PMID: 37970586
The anthelmintic drug praziquantel remains a key clinical therapy for treating various diseases caused by parasitic flatworms. The parasite target of praziquantel has remained undefined despite longstanding usage in the...
7.
Sprague D, Park S, Gramberg S, Bauer L, Rohr C, Chulkov E, et al.
bioRxiv
. 2023 Oct;
PMID: 37790347
Diseases caused by parasitic flatworms impart a considerable healthcare burden worldwide. Many of these diseases - for example, the parasitic blood fluke infection, schistosomiasis - are treated with the drug...
8.
Jin H, Park S, Yun Y, Song N, Baik S
Microorganisms
. 2023 Sep;
11(9).
PMID: 37764128
Nitric oxide (NO) is a free radical associated with physiological functions such as blood pressure regulation, cardiovascular health, mitochondrial production, calcium transport, oxidative stress, and skeletal muscle repair. This study...
9.
Park S, Jin H, Song N, Baik S
Microorganisms
. 2023 Aug;
11(8).
PMID: 37630480
To understand the biological roles of strains as probiotics isolated from the traditional Korean fermented food, , was selected based on its high cinnamoyl esterase (CE) and antioxidant activities. The...
10.
Kim J, Park S, Lee H
PLoS One
. 2023 Aug;
18(8):e0289493.
PMID: 37531332
Additive manufacturing, or 3D printing, has revolutionized the way we create objects. However, its layer-by-layer process may lead to an increased incidence of local defects compared to traditional casting-based methods....