Sanela Smajilovic
Overview
Explore the profile of Sanela Smajilovic including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
560
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0
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Recent Articles
1.
Clemmensen C, Jorgensen C, Smajilovic S, Brauner-Osborne H
Diabetes Obes Metab
. 2016 Dec;
19(4):599-603.
PMID: 27943578
The G protein-coupled receptor GPRC6A (GPCR, Class C, group 6, subtype A) has been proposed to be a sensor for basic L-amino acids that are hypothesized to translate ingestive behaviour...
2.
Jacobsen S, Norskov-Lauritsen L, Thomsen A, Smajilovic S, Wellendorph P, Larsson N, et al.
J Pharmacol Exp Ther
. 2013 Sep;
347(2):298-309.
PMID: 24008333
The GPRC6A receptor is a recently "deorphanized" class C G protein-coupled receptor. We and others have shown that this receptor is coactivated by basic l-α-amino acids and divalent cations, whereas...
3.
Clemmensen C, Smajilovic S, Smith E, Woods S, Brauner-Osborne H, Seeley R, et al.
Endocrinology
. 2013 Aug;
154(11):3978-83.
PMID: 23959939
Pharmacological and surgical interventions that increase glucagon-like peptide 1 (GLP-1) action are effective to improve glucose homeostasis in type 2 diabetes mellitus. In light of this, nutritional strategies to enhance...
4.
Smajilovic S, Wellendorph P, Brauner-Osborne H
Curr Pharm Des
. 2013 Jul;
20(16):2693-702.
PMID: 23886393
A number of nutrient sensing seven trans-membrane (7TM) receptors have been identified and characterized over the past few years. While the sensing mechanisms to carbohydrates and free fatty acids are...
5.
Clemmensen C, Smajilovic S, Madsen A, Klein A, Holst B, Brauner-Osborne H
J Endocrinol
. 2013 Feb;
217(2):151-60.
PMID: 23428581
The recently identified G protein-coupled receptor GPRC6A is activated by dietary amino acids and expressed in multiple tissues. Although the receptor is hypothesised to exert biological impact on metabolic and...
6.
Rossol M, Pierer M, Raulien N, Quandt D, Meusch U, Rothe K, et al.
Nat Commun
. 2012 Dec;
3:1329.
PMID: 23271661
Activation of the NLRP3 inflammasome enables monocytes and macrophages to release high levels of interleukin-1β during inflammatory responses. Concentrations of extracellular calcium can increase at sites of infection, inflammation or...
7.
Smajilovic S, Clemmensen C, Johansen L, Wellendorph P, Holst J, Thams P, et al.
Amino Acids
. 2012 Jun;
44(2):383-90.
PMID: 22714012
GPRC6A is a seven-transmembrane receptor activated by a wide range of L-α-amino acids, most potently by L-arginine and other basic amino acids. The receptor is broadly expressed, but its exact...
8.
Thomsen A, Smajilovic S, Brauner-Osborne H
Curr Drug Targets
. 2012 Jun;
13(10):1324-35.
PMID: 22702634
A hallmark of chronic kidney disease is hyperphosphatemia due to renal phosphate retention. Prolonged parathyroid gland exposure to hyperphosphatemia leads to secondary hyperparathyroidism characterized by hyperplasia of the glands and...
9.
Clemmensen C, Madsen A, Smajilovic S, Holst B, Brauner-Osborne H
Amino Acids
. 2011 Dec;
43(3):1265-75.
PMID: 22200933
L-Arginine (L-Arg) is a conditionally essential amino acid and a natural constituent of dietary proteins. Studies in obese rats and type 2 diabetic humans have indicated that dietary supplementation with...
10.
Smajilovic S, Yano S, Jabbari R, Tfelt-Hansen J
Br J Pharmacol
. 2011 Mar;
164(3):884-93.
PMID: 21410453
Calcium is a crucial second messenger in the cardiovascular system. However, calcium may also be an extracellular first messenger through a G-protein-coupled receptor that senses extracellular concentration (Ca(2+)(o)), the calcium-sensing...