Sandya Ajith
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Explore the profile of Sandya Ajith including associated specialties, affiliations and a list of published articles.
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10
Citations
294
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Recent Articles
1.
Ajith S, Gazzara M, Cole B, Shankarling G, Martinez N, Mallory M, et al.
RNA Biol
. 2016 Apr;
13(6):569-81.
PMID: 27096301
CELF2 is an RNA binding protein that has been implicated in developmental and signal-dependent splicing in the heart, brain and T cells. In the heart, CELF2 expression decreases during development,...
2.
Martinez N, Pan Q, Cole B, Yarosh C, Babcock G, Heyd F, et al.
RNA
. 2012 Mar;
18(5):1029-40.
PMID: 22454538
The formation and execution of a productive immune response requires the maturation of competent T cells and a robust change in cellular activity upon antigen challenge. Such changes in cellular...
3.
Mattia K, Puffer B, Williams K, Gonzalez R, Murray M, Sluzas E, et al.
PLoS One
. 2011 Nov;
6(11):e27252.
PMID: 22096543
The lack of reliable, high-throughput tools for characterizing anti-dengue virus (DENV) antibodies in large numbers of serum samples has been an obstacle in understanding the impact of neutralizing antibodies on...
4.
Hansen J, Wexler B, Rogers D, Hite K, Panchenko T, Ajith S, et al.
J Biol Chem
. 2011 Apr;
286(21):18938-48.
PMID: 21467044
Mass spectrometry-based hydrogen/deuterium exchange (H/DX) has been used to define the polypeptide backbone dynamics of full-length methyl CpG binding protein 2 (MeCP2) when free in solution and when bound to...
5.
Bassett E, Wood S, Salimian K, Ajith S, Foltz D, Black B
J Cell Biol
. 2010 Jul;
190(2):177-85.
PMID: 20643881
The nearly ubiquitous presence of repetitive centromere DNA sequences across eukaryotic species is in paradoxical contrast to their apparent functional dispensability. Centromeric chromatin is spatially delineated into the kinetochore-forming array...
6.
Gopi H, Cocklin S, Pirrone V, McFadden K, Tuzer F, Zentner I, et al.
J Mol Recognit
. 2008 May;
22(2):169-74.
PMID: 18498083
In this work, we identified a high affinity and potency metallocene-containing triazole peptide conjugate that suppresses the interactions of HIV-1 envelope gp120 at both its CD4 and co-receptor binding sites....
7.
McFadden K, Cocklin S, Gopi H, Baxter S, Ajith S, Mahmood N, et al.
Proteins
. 2007 Mar;
67(3):617-29.
PMID: 17348010
The first, critical stage of HIV-1 infection is fusion of viral and host cellular membranes initiated by a viral envelope glycoprotein gp120. We evaluated the potential to form a chimeric...
8.
Cocklin S, Gopi H, Querido B, Nimmagadda M, Kuriakose S, Cicala C, et al.
J Virol
. 2007 Jan;
81(7):3645-8.
PMID: 17251295
The AIDS epidemic continues to spread at an alarming rate worldwide, especially in developing countries. One approach to solving this problem is the generation of anti-human immunodeficiency virus (HIV) compounds...
9.
Click chemistry on azidoproline: high-affinity dual antagonist for HIV-1 envelope glycoprotein gp120
Gopi H, Tirupula K, Baxter S, Ajith S, Chaiken I
ChemMedChem
. 2006 Aug;
1(1):54-7.
PMID: 16892335
No abstract available.
10.
Baxter S, Panarello D, Ajith S, Bhattacharya M, Chaiken I
Biotechnol Appl Biochem
. 2006 Jul;
45(Pt 3):167-72.
PMID: 16872272
Here, we demonstrate for the first time that the hollow-fibre bioreactor is an excellent tool for the production of Drosophila-expressed recombinant proteins. Using the example of the soluble extracellular portion...