Sandra Weller
Overview
Explore the profile of Sandra Weller including associated specialties, affiliations and a list of published articles.
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38
Citations
1457
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Recent Articles
1.
Beigl T, Paul A, Fellmeth T, Nguyen D, Barber L, Weller S, et al.
EMBO Rep
. 2024 Jul;
25(9):3896-3924.
PMID: 39048751
The Bcl-2 family controls apoptosis by direct interactions of pro- and anti-apoptotic proteins. The principle mechanism is binding of the BH3 domain of pro-apoptotic proteins to the hydrophobic groove of...
2.
Bopple K, Oren Y, Henry W, Dong M, Weller S, Thiel J, et al.
Cell Death Dis
. 2024 Apr;
15(4):290.
PMID: 38658567
High-grade serous ovarian cancer (HGSOC) represents the most common and lethal subtype of ovarian cancer. Despite initial response to platinum-based standard therapy, patients commonly suffer from relapse that likely originates...
3.
Weill J, Weller S, Reynaud C
J Exp Med
. 2023 Oct;
220(11).
PMID: 37824081
Several species generate their preimmune repertoire in gut-associated lymphoid tissues (GALT), compensating a reduced germline V gene repertoire by post-rearrangement diversification mechanisms (gene conversion and/or somatic hypermutation) in these environments...
4.
Weller S, Weill J, Reynaud C
Med Sci (Paris)
. 2023 Jun;
39(6-7):490-492.
PMID: 37387652
No abstract available.
5.
Cox E, El-Behi M, Ries S, Vogt J, Kohlhaas V, Michna T, et al.
Cell Rep
. 2023 Apr;
42(4):112378.
PMID: 37060566
The signals controlling marginal zone (MZ) and follicular (FO) B cell development remain incompletely understood. Here, we show that AKT orchestrates MZ B cell formation in mice and humans. Genetic...
6.
Weller S, Sterlin D, Fadeev T, Coignard E, Verge de Los Aires A, Goetz C, et al.
Sci Immunol
. 2023 Jan;
8(79):eade1413.
PMID: 36706172
Marginal zone (MZ) B cells are one of the main actors of T-independent (TI) responses in mice. To identify the B cell subset(s) involved in such responses in humans, we...
7.
Goodrum F, Lowen A, Lakdawala S, Alwine J, Casadevall A, Imperiale M, et al.
mSphere
. 2023 Jan;
8(2):e0003423.
PMID: 36700653
Viruses have brought humanity many challenges: respiratory infection, cancer, neurological impairment and immunosuppression to name a few. Virology research over the last 60+ years has responded to reduce this disease...
8.
Goodrum F, Lowen A, Lakdawala S, Alwine J, Casadevall A, Imperiale M, et al.
mBio
. 2023 Jan;
14(1):e0018823.
PMID: 36700642
Viruses have brought humanity many challenges: respiratory infection, cancer, neurological impairment and immunosuppression to name a few. Virology research over the last 60+ years has responded to reduce this disease...
9.
Goodrum F, Lowen A, Lakdawala S, Alwine J, Casadevall A, Imperiale M, et al.
J Virol
. 2023 Jan;
97(2):e0008923.
PMID: 36700640
Viruses have brought humanity many challenges: respiratory infection, cancer, neurological impairment and immunosuppression to name a few. Virology research over the last 60+ years has responded to reduce this disease...
10.
Weller S, Toenniessen A, Schaefer B, Beigl T, Muenchow A, Bopple K, et al.
Cell Death Discov
. 2022 Apr;
8(1):215.
PMID: 35443750
Enhanced expression of anti-apoptotic B-cell lymphoma 2 (BCL-2) protein is frequent in cancer. Targeting of BCL-2 with the specific inhibitor ABT-199 (Venetoclax) has significant clinical activity in malignant diseases such...