Sandra Steiner
Overview
Explore the profile of Sandra Steiner including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
23
Citations
482
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0
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Recent Articles
1.
Obst-Sander U, Ricci A, Kuhn B, Friess T, Koldewey P, Kuglstatter A, et al.
J Med Chem
. 2022 Sep;
65(19):13052-13073.
PMID: 36178776
Addressing resistance to third-generation EGFR TKIs such as osimertinib via the EGFR mutation remains a highly unmet need in EGFR-driven non-small-cell lung cancer (NSCLC). Herein, we present the discovery of...
2.
Nolvachai Y, Salzmann S, Zavahir J, Doetzer R, Steiner S, Kulsing C, et al.
Anal Chem
. 2021 Nov;
93(46):15508-15516.
PMID: 34762418
An improved strategy for compound identification incorporating gas chromatography hyphenated with Fourier transform infrared spectroscopy and mass spectroscopy (GC-FTIR/MS) is reported. (Over)reliance on MS may lead either to ambiguous identity...
3.
Fuchs D, Bayer B, Gupta T, Szabo G, Wilhelm R, Eder D, et al.
ACS Appl Mater Interfaces
. 2020 Aug;
12(36):40937-40948.
PMID: 32805835
Graphene electrodes and deep eutectic solvents (DESs) are two emerging material systems that have individually shown highly promising properties in electrochemical applications. To date, however, it has not been tested...
4.
Boselt L, Dotzer R, Steiner S, Stritzinger M, Salzmann S, Riniker S
Anal Chem
. 2020 May;
92(13):9124-9131.
PMID: 32449349
The relative stereochemistry and isomeric substitution pattern of organic molecules is typically determined using nuclear magnetic resonance spectroscopy (NMR). However, NMR spectra are sometimes nonconclusive, e.g., if spectra are extremely...
5.
Gobbi L, Knust H, Korner M, Honer M, Czech C, Belli S, et al.
J Med Chem
. 2017 Jun;
60(17):7350-7370.
PMID: 28654263
Aggregates of tau and beta amyloid (Aβ) plaques constitute the histopathological hallmarks of Alzheimer's disease and are prominent targets for novel therapeutics as well as for biomarkers for diagnostic in...
6.
Klang N, Rowland C, Fried-Oken M, Steiner S, Granlund M, Adolfsson M
Augment Altern Commun
. 2016 Feb;
32(1):41-8.
PMID: 26837187
The aim of the study was to explore the contents of communication-related goals in individualized education programs (IEPs) for students with complex communication needs. Goals in 43 IEPs were linked...
7.
Schoenfeld R, Bourdet D, Brameld K, Chin E, De Vicente J, Fung A, et al.
J Med Chem
. 2013 Sep;
56(20):8163-82.
PMID: 24069953
Hepatitis C virus (HCV) is a major global public health problem. While the current standard of care, a direct-acting antiviral (DAA) protease inhibitor taken in combination with pegylated interferon and...
8.
Buchli B, Waldauer S, Walser R, Donten M, Pfister R, Blochliger N, et al.
Proc Natl Acad Sci U S A
. 2013 Jul;
110(29):11725-30.
PMID: 23818626
By covalently linking an azobenzene photoswitch across the binding groove of a PDZ domain, a conformational transition, similar to the one occurring upon ligand binding to the unmodified domain, can...
9.
Huang D, Rossini E, Steiner S, Caflisch A
ChemMedChem
. 2013 Jun;
9(3):573-9.
PMID: 23804246
Bromodomains are α-helical bundles of approximately 110 residues that recognize acetylated lysine side chains mainly on histone tails. Bromodomains are known to play an important role in cancer and inflammation,...
10.
Steiner S, Magno A, Huang D, Caflisch A
FEBS Lett
. 2013 May;
587(14):2158-63.
PMID: 23711371
Bromodomains are protein modules that selectively recognize histones by binding to acetylated lysines. Here, we have carried out multiple molecular dynamics simulations of 20 human bromodomains to investigate the flexibility...