Sandra Prassl
Overview
Explore the profile of Sandra Prassl including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
115
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0
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Recent Articles
1.
Beckmann K, Reitinger C, Yan X, Carle A, Blumle E, Jurkschat N, et al.
Antibodies (Basel)
. 2024 Apr;
13(2).
PMID: 38651411
The activation of CD40-mediated signaling in antigen-presenting cells is a promising therapeutic strategy to promote immune responses against tumors. Most agonistic anti-CD40 antibodies currently in development require the Fcγ-receptor (FcγR)-mediated...
2.
Wege A, Kirchhammer N, Kazandjian L, Prassl S, Brandt M, Piendl G, et al.
J Transl Med
. 2020 Aug;
18(1):316.
PMID: 32799890
Background: Antibody based cancer therapies have achieved convincing success rates combining enhanced tumor specificity and reduced side effects in patients. Trastuzumab that targets the human epidermal growth factor related receptor...
3.
Jurik A, Hausser E, Kutter S, Pattis I, Prassl S, Weiss E, et al.
Infect Immun
. 2010 Sep;
78(12):5244-51.
PMID: 20876293
Bacterial type IV secretion systems are macromolecule transporters with essential functions for horizontal gene transfer and for symbiotic and pathogenic interactions with eukaryotic host cells. Helicobacter pylori, the causative agent...
4.
Fischer W, Prassl S, Haas R
Curr Top Microbiol Immunol
. 2009 Oct;
337:129-71.
PMID: 19812982
The human gastric pathogen Helicobacter pylori is able to establish an infection in a hostile environment with virtually no competitors. For this purpose, it has elaborated a set of colonization...
5.
Integrin subunit CD18 Is the T-lymphocyte receptor for the Helicobacter pylori vacuolating cytotoxin
Sewald X, Gebert-Vogl B, Prassl S, Barwig I, Weiss E, Fabbri M, et al.
Cell Host Microbe
. 2008 Jan;
3(1):20-9.
PMID: 18191791
Helicobacter pylori infection is associated with gastritis, ulcerations, and gastric adenocarcinoma. H. pylori secretes the vacuolating cytotoxin (VacA), a major pathogenicity factor. VacA has immunosuppressive effects, inhibiting interleukin-2 (IL-2) secretion...