Stephan Fischer
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Explore the profile of Stephan Fischer including associated specialties, affiliations and a list of published articles.
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70
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1503
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Recent Articles
1.
Macmillan D, Ambure P, Aranda V, Bayona Y, Bonderovic V, Dawick J, et al.
Environ Toxicol Chem
. 2025 Feb;
PMID: 39937217
Acute fish toxicity is an ecotoxicological endpoint which provides important information about a chemical's potential to elicit adverse effect(s) on fish. These effects are typically studied using in vivo tests...
2.
Revel M, Groh K, Bertoli J, Degeratu M, Fischer M, Fischer S, et al.
Environ Toxicol Chem
. 2025 Jan;
PMID: 39880375
Given the need to reduce animal testing for environmental risk assessment, we aim to develop a fish invitrome, an alternative fish modular framework capable of predicting chemical toxicity in fish...
3.
Jiang L, Lunding L, Webber W, Beckmann K, Azam T, Falkesgaard Hojen J, et al.
Front Immunol
. 2024 Jul;
15:1427100.
PMID: 38983847
Introduction: Interleukin-18 (IL-18), a pro-inflammatory cytokine belonging to the IL-1 Family, is a key mediator ofautoinflammatory diseases associated with the development of macrophage activation syndrome (MAS).High levels of IL-18 correlate...
4.
Roux de Bezieux H, Street K, Fischer S, Van den Berge K, Chance R, Risso D, et al.
BMC Bioinformatics
. 2024 May;
25(1):198.
PMID: 38789920
Background: Single-cell transcriptome sequencing (scRNA-Seq) has allowed new types of investigations at unprecedented levels of resolution. Among the primary goals of scRNA-Seq is the classification of cells into distinct types....
5.
Chen X, Fischer S, Rue M, Zhang A, Mukherjee D, Kanold P, et al.
Nature
. 2024 Apr;
PMID: 38658747
The cerebral cortex is composed of neuronal types with diverse gene expression that are organized into specialized cortical areas. These areas, each with characteristic cytoarchitecture, connectivity and neuronal activity, are...
6.
Beckmann K, Reitinger C, Yan X, Carle A, Blumle E, Jurkschat N, et al.
Antibodies (Basel)
. 2024 Apr;
13(2).
PMID: 38651411
The activation of CD40-mediated signaling in antigen-presenting cells is a promising therapeutic strategy to promote immune responses against tumors. Most agonistic anti-CD40 antibodies currently in development require the Fcγ-receptor (FcγR)-mediated...
7.
Schmid R, Volcic M, Fischer S, Qu Z, Barth H, Popat A, et al.
Sci Rep
. 2023 Nov;
13(1):20175.
PMID: 37978264
Besides the many advantages of oral drug administration, challenges like premature drug degradation and limited bioavailability in the gastro-intestinal tract (GIT) remain. A prolonged residence time in the GIT is...
8.
Ballouz S, Kawaguchi R, Pena M, Fischer S, Crow M, French L, et al.
Nat Commun
. 2023 Nov;
14(1):7226.
PMID: 37940702
Genetic and environmental variation are key contributors during organism development, but the influence of minor perturbations or noise is difficult to assess. This study focuses on the stochastic variation in...
9.
Yan X, Ols S, Cerveira R, Lenart K, Hellgren F, Ye K, et al.
Cell Mol Life Sci
. 2023 Jun;
80(7):189.
PMID: 37353664
Targeting CD40 by agonistic antibodies used as vaccine adjuvants or for cancer immunotherapy is a strategy to stimulate immune responses. The majority of studied agonistic anti-human CD40 antibodies require crosslinking...
10.
Bajrami D, Fischer S, Barth H, Hossain S, Cioffi N, Mizaikoff B
Molecules
. 2022 Dec;
27(24).
PMID: 36557784
Antimicrobial materials are considered potential alternatives to prevent the development of biofilm-associated contaminations. Concerns regarding synthetic preservatives necessitate the development of innovative and safe natural antimicrobials. In the present study,...