Samy Mohamady
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Explore the profile of Samy Mohamady including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
128
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Recent Articles
11.
Mohamady S, Galal M, Eldehna W, Gutierrez D, Ibrahim H, Elmazar M, et al.
ACS Omega
. 2020 Aug;
5(30):18872-18886.
PMID: 32775889
The vascular endothelial growth factor receptor 2 (VEGFR2) and c-mesenchymal epithelial transition factor (c-Met) are members of receptor tyrosine kinases which have a crucial role in the process of angiogenesis....
12.
Mohamady S, Gibriel A, Ahmed M, Hendy M, Naguib B
Bioorg Chem
. 2020 Feb;
96:103641.
PMID: 32032844
A novel synthetic approach was developed for the synthesis of 3-hydrazinotriazolothiadiazines in just one step from Purpald and phenacyl bromides. They were then selectively tethered to naphthoquinone fragments through hydrazine...
13.
Mohamady S, Ismail M, Mogheith S, Attia Y, Taylor S
Bioorg Chem
. 2019 Dec;
94:103433.
PMID: 31785857
Although hepatocellular carcinoma (HCC)-related mortality has increased over the past decades, treatment options are still very limited, underlining the need for developing new therapeutic strategies. The molecular chaperone heat shock...
14.
Mohamady S, Kralt B, Samwel S, Taylor S
ACS Omega
. 2019 Aug;
3(11):15566-15574.
PMID: 31458212
The pyrazole scaffold is one of the most prevalent and important tool in medicinal chemistry. Here, we report a method for preparing 3,5-diarylpyrazoles in good to excellent yield by reacting...
15.
Mohamady S, Taylor S
Curr Protoc Nucleic Acid Chem
. 2018 Oct;
75(1):e62.
PMID: 30307714
This article describes a straight-forward chemical method for the synthesis of nucleoside-5'-O-tetraphosphates, such as cytosine-, guanosine-, adenosine-, and uridine-5'-O-tetraphosphates, starting from the corresponding nucleoside monophosphates and trimetaphosphate, a readily available...
16.
Mohamady S, Desoky A, Taylor S
Org Lett
. 2017 Sep;
19(19):5495.
PMID: 28937770
No abstract available.
17.
McCluskey G, Mohamady S, Taylor S, Bearne S
Chembiochem
. 2016 Sep;
17(23):2240-2249.
PMID: 27643605
CTP synthase (CTPS) catalyzes the conversion of UTP to CTP and is a target for the development of antiviral, anticancer, antiprotozoal, and immunosuppressive agents. Exposure of cell lines to the...
18.
Mohamady S, Taylor S
Org Lett
. 2016 Jan;
18(3):580-3.
PMID: 26759914
Chemists have been attempting to triphosphorylate nucleosides and other alcohols using trimetaphosphate (TriMP) since the 1960s. However, this route appears to have been abandoned due to poor yields. The first...
19.
Ayoub B, Mohamady S, Hendy M, Elmazar M
Int J Biomed Sci
. 2016 Jan;
11(4):185-9.
PMID: 26759535
Development of enhanced UPLC-UV method for determination of nicotine in human plasma was achieved on a Symmetry(®) C18 column (100 mm × 2.1 mm, 2.2 μm) applying isocratic elution based...
20.
Mohamady S, Taylor S
J Org Chem
. 2014 Feb;
79(5):2308-13.
PMID: 24552623
2'-Deoxynucleotide 5'-tetraphosphates in which a fluorescent label is attached to the terminal phosphate are used as key reagents in high-throughput DNA sequencing techniques and in single nucleotide polymorphism typing assays....