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Samuel Rabkin

Explore the profile of Samuel Rabkin including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 147
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Recent Articles
1.
Aghi M, Liu T, Rabkin S, Martuza R
Mol Ther . 2008 Oct; 17(1):51-6. PMID: 18957963
Hypoxia contributes to the resistance of tumors to conventional therapies. We hypothesized that their replication in hypoxic environments like brain or oral mucosa would make oncolytic herpes simplex viruses (HSVs)...
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Messerli S, Prabhakar S, Tang Y, Mahmood U, Giovannini M, Weissleder R, et al.
Hum Gene Ther . 2006 Jan; 17(1):20-30. PMID: 16409122
Gene therapy for schwannomas was evaluated in two mouse models of neurofibromatosis type 2 (NF2): (1) a transgenic model in which mice express a dominant mutant form of merlin and...
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Aghi M, Rabkin S, Martuza R
J Natl Cancer Inst . 2006 Jan; 98(1):38-50. PMID: 16391370
Background: Gliomas treated with the alkylating agent temozolomide have incomplete responses in part because of tumoral repair of chemotherapy-induced DNA damage. Data from phase I trials suggest that G207, an...
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Aghi M, Rabkin S
Curr Opin Mol Ther . 2005 Oct; 7(5):419-30. PMID: 16248277
Established treatments such as surgery, radiation and chemotherapy have not altered the median survival of glioblastoma, the most common malignant brain tumor. Since these failures reflect the highly invasive nature...