Samuel Kakraba
Overview
Explore the profile of Samuel Kakraba including associated specialties, affiliations and a list of published articles.
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5
Citations
67
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Recent Articles
1.
Kakraba S, Ayyadevara S, Mainali N, Balasubramaniam M, Bowroju S, Penthala N, et al.
Pharmaceuticals (Basel)
. 2023 Oct;
16(10).
PMID: 37895969
Chronic, low-grade inflammation has been implicated in aging and age-dependent conditions, including Alzheimer's disease, cardiomyopathy, and cancer. One of the age-associated processes underlying chronic inflammation is protein aggregation, which is...
2.
Bowroju S, Mainali N, Ayyadevara S, Penthala N, Krishnamachari S, Kakraba S, et al.
Molecules
. 2020 Aug;
25(16).
PMID: 32784464
A series of novel hybrid 8-hydroxyquinoline-indole derivatives (, and ) were synthesized and screened for inhibitory activity against self-induced and metal-ion induced Aβ aggregation as potential treatments for Alzheimer's disease...
3.
Kakraba S, Ayyadevara S, Penthala N, Balasubramaniam M, Ganne A, Liu L, et al.
Front Mol Neurosci
. 2020 Jan;
12:310.
PMID: 31920540
Age-progressive neurodegenerative pathologies, including Alzheimer's disease (AD), are distinguished and diagnosed by disease-specific components of intra- or extra-cellular aggregates. Increasing evidence suggests that neuroinflammation promotes protein aggregation, and is involved...
4.
Balasubramaniam M, Ayyadevara S, Ganne A, Kakraba S, Penthala N, Du X, et al.
iScience
. 2019 Oct;
20:248-264.
PMID: 31593839
Diagnosis of neurodegenerative diseases hinges on "seed" proteins detected in disease-specific aggregates. These inclusions contain diverse constituents, adhering through aberrant interactions that our prior data indicate are nonrandom. To define...
5.
Ayyadevara S, Balasubramaniam M, Kakraba S, Alla R, Mehta J, Shmookler Reis R
Antioxid Redox Signal
. 2017 May;
27(17):1383-1396.
PMID: 28537433
Aims: Many progressive neurological disorders, including Alzheimer's disease (AD), Huntington's disease, and Parkinson's disease (PD), are characterized by accumulation of insoluble protein aggregates. In prospective trials, the cyclooxygenase inhibitor aspirin...