Adam H Marblestone
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Explore the profile of Adam H Marblestone including associated specialties, affiliations and a list of published articles.
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19
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1409
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Recent Articles
1.
Shin T, Wang H, Zhang C, An B, Lu Y, Zhang E, et al.
Nat Commun
. 2025 Feb;
16(1):1579.
PMID: 39939319
Lipid membranes are key to the nanoscale compartmentalization of biological systems, but fluorescent visualization of them in intact tissues, with nanoscale precision, is challenging to do with high labeling density....
2.
Shin T, Wang H, Zhang C, An B, Lu Y, Zhang E, et al.
bioRxiv
. 2024 Mar;
PMID: 38496681
Lipid membranes are key to the nanoscale compartmentalization of biological systems, but fluorescent visualization of them in intact tissues, with nanoscale precision, is challenging to do with high labeling density....
3.
Alon S, Goodwin D, Sinha A, Wassie A, Chen F, Daugharthy E, et al.
Science
. 2021 Jan;
371(6528).
PMID: 33509999
Methods for highly multiplexed RNA imaging are limited in spatial resolution and thus in their ability to localize transcripts to nanoscale and subcellular compartments. We adapt expansion microscopy, which physically...
4.
Boyden E, Marblestone A
Neuron
. 2019 May;
102(3):523-525.
PMID: 31071286
How can engineers help invent tools for neuroscience? We here explore a model for how engineers can choose problems and map out possible technologies that help address them. We also...
5.
Rodriques S, Marblestone A, Boyden E
PLoS One
. 2019 Mar;
14(3):e0212868.
PMID: 30921350
We propose and theoretically study an approach to massively parallel single molecule peptide sequencing, based on single molecule measurement of the kinetics of probe binding (Havranek, et al., 2013) to...
6.
Oran D, Rodriques S, Gao R, Asano S, Skylar-Scott M, Chen F, et al.
Science
. 2018 Dec;
362(6420):1281-1285.
PMID: 30545883
Lithographic nanofabrication is often limited to successive fabrication of two-dimensional (2D) layers. We present a strategy for the direct assembly of 3D nanomaterials consisting of metals, semiconductors, and biomolecules arranged...
7.
de Paz A, Cybulski T, Marblestone A, Zamft B, Church G, Boyden E, et al.
Nucleic Acids Res
. 2018 May;
46(13):e78.
PMID: 29718339
DNA polymerase fidelity is affected by both intrinsic properties and environmental conditions. Current strategies for measuring DNA polymerase error rate in vitro are constrained by low error subtype sensitivity, poor...
8.
Marblestone A, Wayne G, Kording K
Behav Brain Sci
. 2018 Jan;
40:e272.
PMID: 29342693
Lake et al. suggest that current AI systems lack the inductive biases that enable human learning. However, Lake et al.'s proposed biases may not directly map onto mechanisms in the...
9.
Yoon Y, Dai P, Wohlwend J, Chang J, Marblestone A, Boyden E
Front Comput Neurosci
. 2017 Nov;
11:97.
PMID: 29114215
We here introduce and study the properties, via computer simulation, of a candidate automated approach to algorithmic reconstruction of dense neural morphology, based on simulated data of the kind that...
10.
Wu J, de Paz A, Zamft B, Marblestone A, Boyden E, Kording K, et al.
Sci Rep
. 2017 Jul;
7(1):4756.
PMID: 28684739
DNA polymerase (pol) processivity, i.e., the bases a polymerase extends before falling off the DNA, and activity are important for copying difficult DNA sequences, including simple repeats. Y-family pols would...