Samuel Demharter
Overview
Explore the profile of Samuel Demharter including associated specialties, affiliations and a list of published articles.
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Articles
25
Citations
486
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Recent Articles
11.
Zaghet N, Madsen K, Rossi F, Perez D, Amendola P, Demharter S, et al.
Cell Rep
. 2021 Nov;
37(8):110050.
PMID: 34818537
Germ cells have evolved unique mechanisms to ensure the transmission of genetically and nongenetically encoded information, whose alteration compromises germ cell immortality. Chromatin factors play fundamental roles in these mechanisms....
12.
Nohr A, Lindow M, Forsingdal A, Demharter S, Nielsen T, Buller R, et al.
Neuropsychopharmacology
. 2021 Apr;
46(7):1324-1332.
PMID: 33833401
A better understanding of the biological factors underlying antidepressant treatment in patients with major depressive disorder (MDD) is needed. We perform gene expression analyses and explore sources of variability in...
13.
Pfisterer U, Petukhov V, Demharter S, Meichsner J, Thompson J, Batiuk M, et al.
Nat Commun
. 2020 Nov;
11(1):5988.
PMID: 33214565
A Correction to this paper has been published: https://doi.org/10.1038/s41467-020-19869-5.
14.
Pfisterer U, Petukhov V, Demharter S, Meichsner J, Thompson J, Batiuk M, et al.
Nat Commun
. 2020 Oct;
11(1):5038.
PMID: 33028830
Epilepsy is one of the most common neurological disorders, yet its pathophysiology is poorly understood due to the high complexity of affected neuronal circuits. To identify dysfunctional neuronal subtypes underlying...
15.
Sanz-Morello B, Pfisterer U, Hansen N, Demharter S, Thakur A, Fujii K, et al.
EMBO J
. 2020 Aug;
39(18):e105759.
PMID: 32744742
Parvalbumin-positive (PV ) fast-spiking interneurons are essential to control the firing activity of principal neuron ensembles, thereby regulating cognitive processes. The high firing frequency activity of PV interneurons imposes high-energy...
16.
Barkas N, Petukhov V, Nikolaeva D, Lozinsky Y, Demharter S, Khodosevich K, et al.
Nat Methods
. 2019 Jul;
16(8):695-698.
PMID: 31308548
Single-cell RNA sequencing is often applied in study designs that include multiple individuals, conditions or tissues. To identify recurrent cell subpopulations in such heterogeneous collections, we developed Conos, an approach...
17.
Guiu J, Hannezo E, Yui S, Demharter S, Ulyanchenko S, Maimets M, et al.
Nature
. 2019 May;
570(7759):107-111.
PMID: 31092921
Adult intestinal stem cells are located at the bottom of crypts of Lieberkühn, where they express markers such as LGR5 and fuel the constant replenishment of the intestinal epithelium. Although...
18.
Demharter S, Knapp B, Deane C, Minary P
J Chem Inf Model
. 2019 May;
59(6):2894-2899.
PMID: 31070900
MHC class II molecules bind peptides derived from extracellular proteins that have been ingested by antigen-presenting cells and display them to the immune system. Peptide loading occurs within the antigen-presenting...
19.
Adorjan I, Tyler T, Bhaduri A, Demharter S, Finszter C, Bako M, et al.
J Anat
. 2019 Jan;
235(3):543-554.
PMID: 30644551
Neuroserpin is a serine-protease inhibitor mainly expressed in the CNS and involved in the inhibition of the proteolytic cascade. Animal models confirmed its neuroprotective role in perinatal hypoxia-ischaemia and adult...
20.
Krawczyk K, Demharter S, Knapp B, Deane C, Minary P
Bioinformatics
. 2017 Oct;
34(1):41-48.
PMID: 29028987
Availability And Implementation: The code together with examples and tutorials are available from http://www.cs.ox.ac.uk/mosaics. Contact: peter.minary@cs.ox.ac.uk. Supplementary Information: Supplementary data are available at Bioinformatics online.