Samir Wadhawan
Overview
Explore the profile of Samir Wadhawan including associated specialties, affiliations and a list of published articles.
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9
Citations
518
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Recent Articles
1.
Szustakowski J, Balasubramanian S, Kvikstad E, Khalid S, Bronson P, Sasson A, et al.
Nat Genet
. 2021 Jun;
53(7):942-948.
PMID: 34183854
The UK Biobank Exome Sequencing Consortium (UKB-ESC) is a private-public partnership between the UK Biobank (UKB) and eight biopharmaceutical companies that will complete the sequencing of exomes for all ~500,000...
2.
SOMAscan Proteomics Identifies Serum Biomarkers Associated With Liver Fibrosis in Patients With NASH
Luo Y, Wadhawan S, Greenfield A, Decato B, Oseini A, Collen R, et al.
Hepatol Commun
. 2021 May;
5(5):760-773.
PMID: 34027267
Nonalcoholic steatohepatitis (NASH) is a major cause of liver-related morbidity and mortality worldwide. Liver fibrosis stage, a key component of NASH, has been linked to the risk of mortality and...
3.
Sangro B, Melero I, Wadhawan S, Finn R, Abou-Alfa G, Cheng A, et al.
J Hepatol
. 2020 Jul;
73(6):1460-1469.
PMID: 32710922
Background & Aims: Nivolumab, a programmed death (PD)-1 (PD-1) inhibitor, led to durable responses, manageable safety, and increased survival in patients with advanced hepatocellular carcinoma (HCC). In our retrospective analysis,...
4.
Wadhawan S, Pant S, Golhar R, Kirov S, Thompson J, Jacobsen L, et al.
Neurol Genet
. 2017 Dec;
3(6):e207.
PMID: 29264398
Objective: To examine the incidence of nonsynonymous missense variants in (Na1.7), (Na1.8), and (Na1.9) in patients with painful and nonpainful peripheral neuropathy. Methods: Next-generation sequencing was performed on 457 patient...
5.
Wadhawan S, Runz H, Burchard J
Biochem Pharmacol
. 2015 Feb;
94(4):229-40.
PMID: 25707983
The majority of compounds that enter clinical trials fail to meet regulatory standards for marketed therapeutics. Success in clinical trials is increased when therapies are directed against targets for which...
6.
Kosakovsky Pond S, Wadhawan S, Chiaromonte F, Ananda G, Chung W, Taylor J, et al.
Genome Res
. 2009 Oct;
19(11):2144-53.
PMID: 19819906
How many species inhabit our immediate surroundings? A straightforward collection technique suitable for answering this question is known to anyone who has ever driven a car at highway speeds. The...
7.
Wadhawan S, Dickins B, Nekrutenko A
Mol Biol Evol
. 2008 Oct;
25(12):2745-57.
PMID: 18842685
The Gnas and Gnal loci, which encode the alpha subunits of stimulatory G-proteins, are among the most complex eukaryotic genes. They combine elaborate patterns of imprinting, alternative splicing, and antisense...
8.
Chung W, Wadhawan S, Szklarczyk R, Kosakovsky Pond S, Nekrutenko A
PLoS Comput Biol
. 2007 May;
3(5):e91.
PMID: 17511511
Coding of multiple proteins by overlapping reading frames is not a feature one would associate with eukaryotic genes. Indeed, codependency between codons of overlapping protein-coding regions imposes a unique set...
9.
Nekrutenko A, Wadhawan S, Goetting-Minesky P, Makova K
PLoS Genet
. 2005 Aug;
1(2):e18.
PMID: 16110341
XLalphas and ALEX are structurally unrelated mammalian proteins translated from alternative overlapping reading frames of a single transcript. Not only are they encoded by the same locus, but a specific...