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Sami T Tuomivaara

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Articles 14
Citations 199
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Recent Articles
1.
Tuomivaara S, Teo C, Jan Y, Wiita A, Jan L
Commun Biol . 2024 Aug; 7(1):1060. PMID: 39210032
To facilitate our understanding of proteome dynamics during signaling events, robust workflows affording fast time resolution without confounding factors are essential. We present Surface-exposed protein Labeling using PeroxidaSe, HO, and...
2.
Tuomivaara S, Fisher S, Hall S, Goin D, Mattis A, Den Besten P
Environ Health . 2024 Jul; 23(1):66. PMID: 39044276
Background: Fluoride exposure during pregnancy has been associated with various effects on offspring, including changes in behavior and IQ. To provide clues to possible mechanisms by which fluoride may affect...
3.
Robinson J, Das S, Khan W, Khanam R, Price J, Rahman A, et al.
Am J Obstet Gynecol . 2024 May; 232(2):230.e1-230.e19. PMID: 38697337
Background: The Multi-Omics for Mothers and Infants consortium aims to improve birth outcomes. Preterm birth is a major obstetrical complication globally and causes significant infant and childhood morbidity and mortality....
4.
Tuomivaara S, Goin D, Fisher S, Hall S, Mattis A, Den Besten P
Res Sq . 2024 Mar; PMID: 38464284
Background: Fluoride exposure during pregnancy has been associated with various effects on offspring, including changes in behavior and IQ. To provide clues to possible mechanisms by which fluoride affects human...
5.
Pham T, Kim J, Tuomivaara S, Lee Y, Kim S, Wells L, et al.
Anal Chim Acta . 2024 Jan; 1288:342114. PMID: 38220268
Mass spectrometry-based approaches encompass a powerful collection of tools for the analysis biological molecules, including glycans and glycoconjugates. Unlike most traditional bioanalytical methods focusing on these molecules, mass spectrometry is...
6.
Tuomivaara S, Teo C, Jan Y, Jan L, Wiita A
bioRxiv . 2023 Mar; PMID: 36993417
To facilitate our understanding of the often rapid and nuanced dynamics of extracellularly exposed proteomes during signaling events, it is important to devise robust workflows affording fast time resolution without...
7.
Ferguson I, Lin Y, Lam C, Shao H, Tharp K, Hale M, et al.
Cell Chem Biol . 2022 Jul; 29(8):1288-1302.e7. PMID: 35853457
Proteasome inhibitor (PI) resistance remains a central challenge in multiple myeloma. To identify pathways mediating resistance, we first mapped proteasome-associated genetic co-dependencies. We identified heat shock protein 70 (HSP70) chaperones...
8.
Ferguson I, Patino-Escobar B, Tuomivaara S, Lin Y, Nix M, Leung K, et al.
Nat Commun . 2022 Jul; 13(1):4121. PMID: 35840578
The myeloma surface proteome (surfaceome) determines tumor interaction with the microenvironment and serves as an emerging arena for therapeutic development. Here, we use glycoprotein capture proteomics to define the myeloma...
9.
Tuomivaara S, Schliekelman P, Nairn A, Moremen K, York W
Anal Chim Acta . 2017 Oct; 993:22-37. PMID: 29078952
Motivated by the lack of easily implementable and generally applicable strategies to increase and assess data accuracy, we devised a novel label-free approach, termed REQUIEM, to address challenges in relative...
10.
Urbanowicz B, Bharadwaj V, Alahuhta M, Pena M, Lunin V, Bomble Y, et al.
Plant J . 2017 Jul; 91(6):931-949. PMID: 28670741
The mechanistic underpinnings of the complex process of plant polysaccharide biosynthesis are poorly understood, largely because of the resistance of glycosyltransferase (GT) enzymes to structural characterization. In Arabidopsis thaliana, a...