Samantha Perez-Miller
Overview
Explore the profile of Samantha Perez-Miller including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
41
Citations
696
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Tang C, Gomez K, Chen Y, Allen H, Hestehave S, Rodriguez-Palma E, et al.
J Clin Invest
. 2024 Dec;
135(4).
PMID: 39656529
Antagonists - such as Ziconotide and Gabapentin - of the CaV2.2 (N-type) calcium channels are used clinically as analgesics for chronic pain. However, their use is limited by narrow therapeutic...
2.
Perez-Miller S, Gomez K, Khanna R
ACS Pharmacol Transl Sci
. 2024 Jul;
7(7):1916-1936.
PMID: 39022365
Ion channels serve pleiotropic functions. Often found in complexes, their activities and functions are sculpted by auxiliary proteins. We discovered that collapsin response mediator protein 2 (CRMP2) is a binding...
3.
Tang C, Duran P, Calderon-Rivera A, Loya-Lopez S, Gomez K, Perez-Miller S, et al.
PNAS Nexus
. 2024 Jun;
3(6):pgae222.
PMID: 38894876
-palmitoylation, a reversible lipid post-translational modification, regulates the functions of numerous proteins. Voltage-gated sodium channels (Nas), pivotal in action potential generation and propagation within cardiac cells and sensory neurons, can...
4.
Branigan G, Torrandell-Haro G, Chen S, Shang Y, Perez-Miller S, Mao Z, et al.
iScience
. 2023 Nov;
26(11):108316.
PMID: 38026173
Worldwide, an ever-increasing number of women are prescribed estrogen-modulating therapies (EMTs) for the treatment of breast cancer. In parallel, aging of the global population of women will contribute to risk...
5.
Gomez K, Santiago U, Nelson T, Allen H, Calderon-Rivera A, Hestehave S, et al.
Proc Natl Acad Sci U S A
. 2023 Nov;
120(47):e2305215120.
PMID: 37972067
Transmembrane Ca2.2 (N-type) voltage-gated calcium channels are genetically and pharmacologically validated, clinically relevant pain targets. Clinical block of Ca2.2 (e.g., with Prialt/Ziconotide) or indirect modulation [e.g., with gabapentinoids such as...
6.
Gomez K, Allen H, Duran P, Loya-Lopez S, Calderon-Rivera A, Moutal A, et al.
Pain
. 2023 Oct;
165(4):866-883.
PMID: 37862053
The voltage-gated sodium channel Na V 1.7 is an essential component of human pain signaling. Changes in Na V 1.7 trafficking are considered critical in the development of neuropathic pain....
7.
Zhao P, Tang C, Yang Y, Xiao Z, Perez-Miller S, Zhang H, et al.
PLoS Biol
. 2023 Sep;
21(9):e3002309.
PMID: 37713449
The proton-activated chloride (PAC) channel plays critical roles in ischemic neuron death, but its activation mechanisms remain elusive. Here, we investigated the gating of PAC channels using its novel bifunctional...
8.
Gomez K, Stratton H, Duran P, Loya S, Tang C, Calderon-Rivera A, et al.
Proc Natl Acad Sci U S A
. 2023 Jul;
120(32):e2217800120.
PMID: 37498871
Small molecules directly targeting the voltage-gated sodium channel (VGSC) Na1.7 have not been clinically successful. We reported that preventing the addition of a small ubiquitin-like modifier onto the Na1.7-interacting cytosolic...
9.
Xu Y, Wijeratne E, Calderon-Rivera A, Loya-Lopez S, Perez-Miller S, Khanna R, et al.
ACS Omega
. 2023 Jun;
8(22):20085-20095.
PMID: 37305315
Four new triterpenes, 25-dehydroxy-25-methoxyargentatin C (), 20-hydroxyargentatin C (), 20-hydroxyisoargentatin C (), and 24--argentatin C (), together with 10 known triterpenes (-) were isolated from the aerial parts of ....
10.
Stratton H, Boinon L, Gomez K, Martin L, Duran P, Ran D, et al.
Pain
. 2023 Feb;
164(7):1473-1488.
PMID: 36729125
Vascular endothelial growth factor A (VEGF-A) is a pronociceptive factor that causes neuronal sensitization and pain. We reported that blocking the interaction between the membrane receptor neuropilin 1 (NRP1) and...