Samantha M Prezioso
Overview
Explore the profile of Samantha M Prezioso including associated specialties, affiliations and a list of published articles.
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12
Citations
110
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Recent Articles
1.
Done R, Robertson J, Prezioso S, Goldberg J
bioRxiv
. 2024 Jul;
PMID: 38979315
The opportunistic pathogen causes debilitating lung infections in people with cystic fibrosis, as well as eye, burn, and wound infections in otherwise immunocompetent individuals. Many of 's virulence factors are...
2.
Pena J, Prezioso S, McFarland K, Kambara T, Ramsey K, Deighan P, et al.
Nat Commun
. 2021 Mar;
12(1):1702.
PMID: 33731715
In Pseudomonas aeruginosa the alp system encodes a programmed cell death pathway that is switched on in a subset of cells in response to DNA damage and is linked to...
3.
Travis B, Ramsey K, Prezioso S, Tallo T, Wandzilak J, Hsu A, et al.
Mol Cell
. 2020 Nov;
81(1):139-152.e10.
PMID: 33217319
The bacterium Francisella tularensis (Ft) is one of the most infectious agents known. Ft virulence is controlled by a unique combination of transcription regulators: the MglA-SspA heterodimer, PigR, and the...
4.
Kuiper E, Dey D, LaMore P, Owings J, Prezioso S, Goldberg J, et al.
J Biol Chem
. 2019 Nov;
294(52):20109-20121.
PMID: 31753919
The opportunistic bacterial pathogen is a leading cause of serious infections in individuals with cystic fibrosis, compromised immune systems, or severe burns. adhesion to host epithelial cells is enhanced by...
5.
Prezioso S, Duong D, Kuiper E, Deng Q, Alberti S, Conn G, et al.
Sci Rep
. 2019 Mar;
9(1):3553.
PMID: 30837495
The Pseudomonas aeruginosa methyltransferase EftM trimethylates elongation factor-Tu (EF-Tu) on lysine 5 to form a post-translational modification important for initial bacterial adherence to host epithelial cells. EftM methyltransferase activity is...
6.
Prezioso S, Brown N, Goldberg J
Mol Microbiol
. 2017 Jul;
106(1):22-34.
PMID: 28710887
Elfamycins are a relatively understudied group of antibiotics that target the essential process of translation through impairment of EF-Tu function. For the most part, the utility of these compounds has...
7.
Owings J, Kuiper E, Prezioso S, Meisner J, Varga J, Zelinskaya N, et al.
J Biol Chem
. 2015 Dec;
291(7):3280-90.
PMID: 26677219
Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen that trimethylates elongation factor-thermo-unstable (EF-Tu) on lysine 5. Lysine 5 methylation occurs in a temperature-dependent manner and is generally only seen when P....
8.
Schieltz D, McWilliams L, Kuklenyik Z, Prezioso S, Carter A, Williamson Y, et al.
Toxicon
. 2015 Jan;
95:72-83.
PMID: 25576235
The seeds of the Ricinus communis (Castor bean) plant are the source of the economically important commodity castor oil. Castor seeds also contain the proteins ricin and R. communis agglutinin...
9.
Knaack J, Zhou Y, Abney C, Prezioso S, Magnuson M, Evans R, et al.
Anal Chem
. 2012 Nov;
84(22):10052-7.
PMID: 23126363
We have developed a novel immunomagnetic scavenging technique for extracting cholinesterase inhibitors from aqueous matrixes using biological targeting and antibody-based extraction. The technique was characterized using the organophosphorus nerve agent...
10.
Knaack J, Zhou Y, Abney C, Jacob J, Prezioso S, Hardy K, et al.
Anal Chem
. 2012 Oct;
84(21):9470-7.
PMID: 23083472
An automated high-throughput immunomagnetic separation (IMS) method for diagnosing exposure to the organophosphorus nerve agents (OPNAs) sarin (GB), cyclohexylsarin (GF), VX, and Russian VX (RVX) was developed to increase sample...