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Samantha E Peel

Explore the profile of Samantha E Peel including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 200
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Recent Articles
1.
Sayers E, Peel S, Schantz A, England R, Beano M, Bates S, et al.
Mol Ther . 2019 Aug; 27(11):1950-1962. PMID: 31427168
Lipid nanoparticles have great potential for delivering nucleic-acid-based therapeutics, but low efficiency limits their broad clinical translation. Differences in transfection capacity between in vitro models used for nanoparticle pre-clinical testing...
2.
Liu B, Peel S, Fox J, Hall I
Respir Res . 2010 Dec; 11:168. PMID: 21126331
Background: Agonist stimulation of airway smooth muscle (ASM) results in IP3 mediated Ca2+ release from the sarcoplasmic reticulum followed by the activation of store operated and receptor operated non-selective cation...
3.
Cortijo J, Milara J, Mata M, Donet E, Gavara N, Peel S, et al.
Chem Biol Interact . 2009 Sep; 183(1):25-33. PMID: 19781536
Environmental exposure to nickel is associated to respiratory disorders and potential toxicity in the lung but molecular mechanisms remain incompletely explored. The extracellular Ca(2+)-sensing receptor (CaSR) is widely distributed and...
4.
Peel S, Liu B, Hall I
Am J Respir Cell Mol Biol . 2008 Feb; 38(6):744-9. PMID: 18239188
The initial bronchoconstrictor response of the asthmatic airway depends on airway smooth muscle (ASM) contraction. Intracellular calcium is a key signaling molecule, mediating a number of responses, including proliferation, gene...
5.
Peel S, Liu B, Hall I
Respir Res . 2006 Sep; 7:119. PMID: 16987424
Background: Control of cytosolic calcium plays a key role in airway myocyte function. Changes in intracellular Ca2+ stores can modulate contractile responses, modulate proliferation and regulate synthetic activity. Influx of...