Sam de Blank
Overview
Explore the profile of Sam de Blank including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
110
Followers
0
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Recent Articles
1.
Jeremiasse B, van Ineveld R, Bok V, Kleinnijenhuis M, de Blank S, Alieva M, et al.
EMBO Mol Med
. 2024 Jun;
16(7):1495-1514.
PMID: 38831131
Achieving complete tumor resection is challenging and can be improved by real-time fluorescence-guided surgery with molecular-targeted probes. However, pre-clinical identification and validation of probes presents a lengthy process that is...
2.
Alieva M, Barrera Roman M, de Blank S, Petcu D, Zeeman A, Dautzenberg N, et al.
Nat Protoc
. 2024 Mar;
19(7):2052-2084.
PMID: 38504137
Modeling immuno-oncology by using patient-derived material and immune cell co-cultures can advance our understanding of immune cell tumor targeting in a patient-specific manner, offering leads to improve cellular immunotherapy. However,...
3.
Dekkers J, Alieva M, Cleven A, Keramati F, Wezenaar A, van Vliet E, et al.
Nat Biotechnol
. 2022 Jul;
41(1):60-69.
PMID: 35879361
Extending the success of cellular immunotherapies against blood cancers to the realm of solid tumors will require improved in vitro models that reveal therapeutic modes of action at the molecular...
4.
van Ineveld R, Kleinnijenhuis M, Alieva M, de Blank S, Barrera Roman M, van Vliet E, et al.
Nat Biotechnol
. 2021 Jun;
39(10):1239-1245.
PMID: 34083793
Despite advances in three-dimensional (3D) imaging, it remains challenging to profile all the cells within a large 3D tissue, including the morphology and organization of the many cell types present....
5.
Espejo Valle-Inclan J, Stangl C, de Jong A, van Dessel L, van Roosmalen M, Helmijr J, et al.
Genome Med
. 2021 May;
13(1):86.
PMID: 34006333
Here, we describe a novel approach for rapid discovery of a set of tumor-specific genomic structural variants (SVs), based on a combination of low coverage cancer genome sequencing using Oxford...
6.
Stangl C, de Blank S, Renkens I, Westera L, Verbeek T, Espejo Valle-Inclan J, et al.
Nat Commun
. 2020 Jun;
11(1):2861.
PMID: 32504042
Fusion genes are hallmarks of various cancer types and important determinants for diagnosis, prognosis and treatment. Fusion gene partner choice and breakpoint-position promiscuity restricts diagnostic detection, even for known and...