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Esmee J van Vliet

Explore the profile of Esmee J van Vliet including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 210
Followers 0
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Recent Articles
1.
Jeremiasse B, van Ineveld R, Bok V, Kleinnijenhuis M, de Blank S, Alieva M, et al.
EMBO Mol Med . 2024 Jun; 16(7):1495-1514. PMID: 38831131
Achieving complete tumor resection is challenging and can be improved by real-time fluorescence-guided surgery with molecular-targeted probes. However, pre-clinical identification and validation of probes presents a lengthy process that is...
2.
Dekkers J, Alieva M, Cleven A, Keramati F, Wezenaar A, van Vliet E, et al.
Nat Biotechnol . 2022 Jul; 41(1):60-69. PMID: 35879361
Extending the success of cellular immunotherapies against blood cancers to the realm of solid tumors will require improved in vitro models that reveal therapeutic modes of action at the molecular...
3.
van Ineveld R, van Vliet E, Wehrens E, Alieva M, Rios A
EMBO J . 2022 Apr; 41(10):e109675. PMID: 35403737
Our understanding of the cellular composition and architecture of cancer has primarily advanced using 2D models and thin slice samples. This has granted spatial information on fundamental cancer biology and...
4.
van Ineveld R, Kleinnijenhuis M, Alieva M, de Blank S, Barrera Roman M, van Vliet E, et al.
Nat Biotechnol . 2021 Jun; 39(10):1239-1245. PMID: 34083793
Despite advances in three-dimensional (3D) imaging, it remains challenging to profile all the cells within a large 3D tissue, including the morphology and organization of the many cell types present....
5.
Picco G, Cattaneo C, van Vliet E, Crisafulli G, Rospo G, Consonni S, et al.
Cancer Discov . 2021 Apr; 11(8):1923-1937. PMID: 33837064
Targeted therapies, chemotherapy, and immunotherapy are used to treat patients with mismatch repair-deficient (dMMR)/microsatellite instability-high (MSI-H) colorectal cancer. The clinical effectiveness of targeted therapy and chemotherapy is limited by resistance...
6.
Dekkers J, van Vliet E, Sachs N, Rosenbluth J, Kopper O, Rebel H, et al.
Nat Protoc . 2021 Mar; 16(4):1936-1965. PMID: 33692550
Organoid technology has revolutionized the study of human organ development, disease and therapy response tailored to the individual. Although detailed protocols are available for the generation and long-term propagation of...