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Sally-Ann Clark

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Articles 13
Citations 755
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Recent Articles
1.
Li R, Colombo M, Wang G, Rodriguez-Romera A, Benlabiod C, Jooss N, et al.
Sci Transl Med . 2024 Oct; 16(768):eadj7552. PMID: 39383242
Myeloproliferative neoplasms are stem cell-driven cancers associated with a large burden of morbidity and mortality. Most patients present with early-stage disease, but a substantial proportion progress to myelofibrosis or secondary...
2.
Aksoz M, Gafencu G, Stoilova B, Buono M, Zhang Y, Turkalj S, et al.
Sci Immunol . 2024 Aug; 9(98):eadk3469. PMID: 39178276
Hematopoietic stem cells (HSCs) reconstitute multilineage human hematopoiesis after clinical bone marrow (BM) transplantation and are the cells of origin of some hematological malignancies. Although HSCs provide multilineage engraftment, individual...
3.
Hamid M, Cespedes P, Jin C, Chen J, Gileadi U, Antoun E, et al.
Nat Immunol . 2024 Apr; 25(5):834-846. PMID: 38561495
Cancer remains one of the leading causes of mortality worldwide, leading to increased interest in utilizing immunotherapy strategies for better cancer treatments. In the past decade, CD103 T cells have...
4.
Yin Z, Chen J, Lu Y, Wang B, Godfrey L, Mentzer A, et al.
Cell Rep . 2023 May; 42(5):112470. PMID: 37141092
Most existing studies characterizing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific T cell responses are peptide based. This does not allow evaluation of whether tested peptides are processed and presented...
5.
Sousos N, Ni Leathlobhair M, Karali C, Louka E, Bienz N, Royston D, et al.
Nat Med . 2022 May; 28(6):1207-1211. PMID: 35637336
The latency between acquisition of an initiating somatic driver mutation by a single-cell and clinical presentation with cancer is largely unknown. We describe a remarkable case of monozygotic twins presenting...
6.
Scott C, Bartolovic K, Clark S, Waithe D, Hill Q, Okoli S, et al.
Br J Haematol . 2022 Apr; 198(1):e10-e14. PMID: 35417566
No abstract available.
7.
Rodriguez-Meira A, Buck G, Clark S, Povinelli B, Alcolea V, Louka E, et al.
Mol Cell . 2019 Feb; 73(6):1292-1305.e8. PMID: 30765193
Single-cell RNA sequencing (scRNA-seq) has emerged as a powerful tool for resolving transcriptional heterogeneity. However, its application to studying cancerous tissues is currently hampered by the lack of coverage across...
8.
Duarte S, Woll P, Buza-Vidas N, Chin D, Boukarabila H, Luis T, et al.
Blood . 2018 Jan; 131(15):1712-1719. PMID: 29339402
Although an essential role for canonical Notch signaling in generation of hematopoietic stem cells in the embryo and in thymic T-cell development is well established, its role in adult bone...
9.
Mead A, Neo W, Barkas N, Matsuoka S, Giustacchini A, Facchini R, et al.
J Exp Med . 2017 Jun; 214(7):2005-2021. PMID: 28637883
Although previous studies suggested that the expression of FMS-like tyrosine kinase 3 (Flt3) initiates downstream of mouse hematopoietic stem cells (HSCs), internal tandem duplications ( ITDs) have recently been suggested...
10.
Page E, Greathead L, Metcalf R, Clark S, Hart M, Fuchs D, et al.
J Acquir Immune Defic Syndr . 2014 Oct; 67(3):227-35. PMID: 25314246
Background: Immune activation plays a key role in the immunopathogenesis of HIV-1 infection. Microbial translocation, secondary to loss of epithelial integrity and mucosal immune deficiency, is believed to contribute to...