Sailay Siddiqi
Overview
Explore the profile of Sailay Siddiqi including associated specialties, affiliations and a list of published articles.
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Articles
24
Citations
525
Followers
0
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Recent Articles
1.
Somers T, Siddiqi S, Janssen M, Morshuis W, Maas R, Buikema J, et al.
Biomed Pharmacother
. 2024 Sep;
180:117492.
PMID: 39326098
Objectives And Background: The success of statin therapy in reducing cardiovascular morbidity and mortality is contrasted by the skeletal muscle complaints, which often leads to nonadherence. Previous studies have shown...
2.
Somers T, Siddiqi S, Maas R, Sluijter J, Buikema J, van den Broek P, et al.
Basic Res Cardiol
. 2024 Feb;
119(2):309-327.
PMID: 38305903
Statins are effective drugs in reducing cardiovascular morbidity and mortality by inhibiting cholesterol synthesis. These effects are primarily beneficial for the patient's vascular system. A significant number of statin users...
3.
Somers T, Siddiqi S, Morshuis W, Russel F, Schirris T
J Cardiovasc Dev Dis
. 2023 Oct;
10(10).
PMID: 37887864
Statins inhibit HMG-CoA reductase, the rate-limiting enzyme in cholesterol synthesis, and are the cornerstone of lipid-lowering treatment. They significantly reduce cardiovascular morbidity and mortality. However, musculoskeletal symptoms are observed in...
4.
Somers T, Allard N, Siddiqi S, Janssen M, Hopman M, Morshuis W, et al.
Sci Rep
. 2023 Jun;
13(1):9638.
PMID: 37316639
Drug-induced mitochondrial dysfunction is a common adverse effect, particularly in case of statins-the most prescribed drugs worldwide. These drugs have been shown to inhibit complex III (CIII) of the mitochondrial...
5.
Raso A, Dirkx E, Sampaio-Pinto V, Azzouzi H, Cubero R, Sorensen D, et al.
Nat Commun
. 2022 Aug;
13(1):4977.
PMID: 36008482
No abstract available.
6.
de Wit R, Siddiqi S, Tiemessen D, Snabel R, Veenstra G, Oosterwijk E, et al.
J Cell Mol Med
. 2021 Nov;
25(23):10869-10878.
PMID: 34725901
Tissue engineering (TE) of long tracheal segments is conceptually appealing for patients with inoperable tracheal pathology. In tracheal TE, stem cells isolated from bone marrow or adipose tissue have been...
7.
Raso A, Dirkx E, Sampaio-Pinto V, Azzouzi H, Cubero R, Sorensen D, et al.
Nat Commun
. 2021 Aug;
12(1):4808.
PMID: 34376683
Myocardial regeneration is restricted to early postnatal life, when mammalian cardiomyocytes still retain the ability to proliferate. The molecular cues that induce cell cycle arrest of neonatal cardiomyocytes towards terminally...
8.
Meerman M, Bracco Gartner T, Buikema J, Wu S, Siddiqi S, Bouten C, et al.
Front Cardiovasc Med
. 2021 Mar;
8:631985.
PMID: 33644136
Radiation-induced cardiovascular disease is a well-known complication of radiation exposure. Over the last few years, planning for deep space missions has increased interest in the effects of space radiation on...
9.
Timman S, Siddiqi S, Verhagen A
Ann Thorac Surg
. 2019 Mar;
108(5):1586.
PMID: 30910652
No abstract available.
10.
Alvarez Jr R, Wang B, Quijada P, Avitabile D, Ho T, Shaitrit M, et al.
J Mol Cell Cardiol
. 2018 Dec;
127:154-164.
PMID: 30571978
Rationale: Understanding and manipulating the cardiomyocyte cell cycle has been the focus of decades of research, however the ultimate goal of activating mitotic activity in adult mammalian cardiomyocytes remains elusive...