Saila Holopainen
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Explore the profile of Saila Holopainen including associated specialties, affiliations and a list of published articles.
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11
Citations
72
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Recent Articles
1.
Kouki S, Viitanen S, Koho N, Laurila H, Lilja-Maula L, Holopainen S, et al.
J Vet Intern Med
. 2023 Jan;
37(1):268-276.
PMID: 36655626
Background: Salivary bile acids are used to diagnose extraesophageal reflux (EER) and to evaluate the risk of reflux aspiration that is associated with respiratory diseases in dogs. Objectives: To study...
2.
Holopainen S, Laurila H, Lappalainen A, Rajamaki M, Viitanen S
J Vet Intern Med
. 2022 Jun;
36(4):1202-1210.
PMID: 35702817
Background: Prolonged tissue hypoxia caused by chronic pulmonary disease is commonly regarded as an important mechanism in the development of secondary polycythemia, but little clinical data are available to support...
3.
Kaukonen M, Pettinen I, Wickstrom K, Arumilli M, Donner J, Juhola I, et al.
Hum Genet
. 2021 Feb;
140(11):1569-1579.
PMID: 33606121
Retinitis pigmentosa (RP) is a blinding eye disease affecting nearly two million people worldwide. Dogs are affected with a similar illness termed progressive retinal atrophy (PRA). Lapponian herders (LHs) are...
4.
Maatta M, Laurila H, Holopainen S, Aaltonen K, Lilja-Maula L, Viitanen S, et al.
J Vet Intern Med
. 2020 Dec;
35(1):462-471.
PMID: 33274549
Background: Canine idiopathic pulmonary fibrosis (CIPF) is a chronic, interstitial lung disease that mainly affects West Highland white terriers (WHWTs) and is characterized by excessive deposition of extracellular matrix (ECM)...
5.
Kaukonen M, Quintero I, Mukarram A, Hytonen M, Holopainen S, Wickstrom K, et al.
PLoS Genet
. 2020 Mar;
16(3):e1008659.
PMID: 32150541
Retinitis pigmentosa (RP) is the leading cause of blindness with nearly two million people affected worldwide. Many genes have been implicated in RP, yet in 30-80% of the RP patients...
6.
Mikkola L, Holopainen S, Pessa-Morikawa T, Lappalainen A, Hytonen M, Lohi H, et al.
BMC Genomics
. 2019 Dec;
20(1):1027.
PMID: 31881848
Background: Hip dysplasia and osteoarthritis continue to be prevalent problems in veterinary and human medicine. Canine hip dysplasia is particularly problematic as it massively affects several large-sized breeds and can...
7.
Mikkola L, Holopainen S, Lappalainen A, Pessa-Morikawa T, Augustine T, Arumilli M, et al.
PLoS Genet
. 2019 Jul;
15(7):e1008197.
PMID: 31323019
Canine hip dysplasia is a common, non-congenital, complex and hereditary disorder. It can inflict severe pain via secondary osteoarthritis and lead to euthanasia. An analogous disorder exists in humans. The...
8.
Holopainen S, Rautala E, Lilja-Maula L, Lohi H, Rajamaki M, Lappalainen A
Vet Radiol Ultrasound
. 2019 Jun;
60(5):525-532.
PMID: 31172636
Canine idiopathic pulmonary fibrosis is a chronic, progressive interstitial lung disease particularly prevalent in West Highland White Terriers. In the present prospective pilot study, we evaluated the feasibility of modified...
9.
Maatta O, Laurila H, Holopainen S, Lilja-Maula L, Melamies M, Viitanen S, et al.
J Vet Intern Med
. 2018 Oct;
32(6):2074-2081.
PMID: 30311983
Background: Gastroesophageal reflux and microaspiration (MA) of gastric juice are associated with various human respiratory diseases but not in dogs. Objective: To detect the presence of bile acids in bronchoalveolar...
10.
Holopainen S, Hytonen M, Syrja P, Arumilli M, Jarvinen A, Rajamaki M, et al.
PLoS Genet
. 2017 Feb;
13(2):e1006625.
PMID: 28222102
Acute respiratory distress syndrome (ARDS) is the leading cause of death in critical care medicine. The syndrome is typified by an exaggerated inflammatory response within the lungs. ARDS has been...