Saba Parvez
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Explore the profile of Saba Parvez including associated specialties, affiliations and a list of published articles.
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23
Citations
459
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Recent Articles
1.
Parvez S, Asif M, Ahmad A, Javaid I, Rasheed M, Iftikhar R, et al.
BMC Plant Biol
. 2025 Feb;
25(1):259.
PMID: 40000960
The Oleaceae family, encompassing key genera such as Fraxinus (ash trees), Olea (olives), Jasminum (jasmine), Syringa (lilac), and Forsythia, plays a crucial ecological and economic role. Despite their importance, the...
2.
Ma J, Zhang W, Rahimialiabadi S, Ganesh N, Sun Z, Parvez S, et al.
Biol Open
. 2024 Sep;
13(9).
PMID: 39225039
Here, we introduce 'TICIT', targeted integration by CRISPR-Cas9 and integrase technologies, which utilizes the site-specific DNA recombinase - phiC31 integrase - to insert large DNA fragments into CRISPR-Cas9 target loci....
3.
Nwagbo U, Parvez S, Maschek J, Bernstein P
J Lipid Res
. 2024 Feb;
65(3):100518.
PMID: 38342437
Very-long-chain PUFAs (VLC-PUFAs) are a group of lipids with chain lengths >24 carbons, and the ELOVL4 (elongation of very-long-chain FA-4) enzyme is responsible for vertebrate VLC-PUFA biosynthesis. Studies on the...
4.
Parvez S, Zhang T, Peterson R
Methods Mol Biol
. 2023 Sep;
2707:319-334.
PMID: 37668922
CRISPR-Cas9 is a powerful tool to interrogate gene function in a targeted and systematic manner. Although the technology has been scaled up for large-scale genetic screens in cell culture, similar...
5.
Huang K, Poganik J, Parvez S, Raja S, Miller B, Long M, et al.
Nat Protoc
. 2023 Jun;
18(10):3155.
PMID: 37340167
No abstract available.
6.
Huang K, Ly P, Poganik J, Parvez S, Long M, Aye Y
J Vis Exp
. 2023 Jun;
(196).
PMID: 37335096
Reactive metabolites and related electrophilic drugs are among the most challenging small molecules to study. Conventional approaches to deconstruct the mode of action (MOA) of such molecules leverage bulk treatment...
7.
Parvez S, Brandt Z, Peterson R
Nat Protoc
. 2023 Apr;
18(6):1841-1865.
PMID: 37069311
The zebrafish is a powerful model system for studying animal development, for modeling genetic diseases, and for large-scale in vivo functional genetics. Because of its ease of use and its...
8.
Huang K, Poganik J, Parvez S, Raja S, Miller B, Long M, et al.
Nat Protoc
. 2023 Apr;
18(5):1379-1415.
PMID: 37020146
This Protocol Extension describes the adaptation of an existing Protocol detailing the use of targetable reactive electrophiles and oxidants, an on-demand redox targeting toolset in cultured cells. The adaptation described...
9.
Van Hall-Beauvais A, Poganik J, Huang K, Parvez S, Zhao Y, Lin H, et al.
Elife
. 2022 Oct;
11.
PMID: 36300632
Studying electrophile signaling is marred by difficulties in parsing changes in pathway flux attributable to on-target, vis-à-vis off-target, modifications. By combining bolus dosing, knockdown, and Z-REX-a tool investigating on-target/on-pathway electrophile...
10.
Poganik J, Huang K, Parvez S, Zhao Y, Raja S, Long M, et al.
Nat Commun
. 2021 Oct;
12(1):5736.
PMID: 34593792
Despite the emerging importance of reactive electrophilic drugs, deconvolution of their principal targets remains difficult. The lack of genetic tractability/interventions and reliance on secondary validation using other non-specific compounds frequently...