Sa Kan Yoo
Overview
Explore the profile of Sa Kan Yoo including associated specialties, affiliations and a list of published articles.
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Articles
24
Citations
1204
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Recent Articles
1.
Tomita-Naito S, Sulekh S, Yoo S
iScience
. 2024 Oct;
27(9):110793.
PMID: 39371074
During aging, tissue stem cells can demonstrate two opposing phenotypes of tissue homeostasis disruption: proliferation and exhaustion. Stem cells can exhaust as a result of excessive cell proliferation or independently...
2.
Sakizli U, Takano T, Yoo S
PLoS Biol
. 2024 Mar;
22(3):e3002549.
PMID: 38502638
Sugar metabolism plays a pivotal role in sustaining life. Its dynamics within organisms is less understood compared to its intracellular metabolism. Galactose, a hexose stereoisomer of glucose, is a monosaccharide...
3.
Sulekh S, Ikegawa Y, Naito S, Oji A, Hiratani I, Yoo S
Life Sci Alliance
. 2024 Jan;
7(4).
PMID: 38296349
Cell death and proliferation are at a glance dichotomic events, but occasionally coupled. Caspases, traditionally known to execute apoptosis, play non-apoptotic roles, but their exact mechanism remains elusive. Here, using...
4.
Nishida H, Albero A, Onoue K, Ikegawa Y, Sulekh S, Sakizli U, et al.
Biol Open
. 2023 Dec;
13(1).
PMID: 38156558
Historically, necrosis has been considered a passive process, which is induced by extreme stress or damage. However, recent findings of necroptosis, a programmed form of necrosis, shed a new light...
5.
Okada M, Takano T, Ikegawa Y, Ciesielski H, Nishida H, Yoo S
EMBO J
. 2023 May;
42(12):e111383.
PMID: 37140455
Cancer exerts pleiotropic, systemic effects on organisms, leading to health deterioration and eventually to organismal death. How cancer induces systemic effects on remote organs and the organism itself still remains...
6.
Ikegawa Y, Combet C, Groussin M, Navratil V, Safar-Remali S, Shiota T, et al.
EMBO J
. 2023 Feb;
42(8):e110454.
PMID: 36727601
Cells need to sense stresses to initiate the execution of the dormant cell death program. Since the discovery of the first BH3-only protein Bad, BH3-only proteins have been recognized as...
7.
Ciesielski H, Nishida H, Takano T, Fukuhara A, Otani T, Ikegawa Y, et al.
PLoS Biol
. 2022 Apr;
20(4):e3001586.
PMID: 35468130
Many adult tissues are composed of differentiated cells and stem cells, each working in a coordinated manner to maintain tissue homeostasis during physiological cell turnover. Old differentiated cells are believed...
8.
9.
Nishida H, Okada M, Yang L, Takano T, Tabata S, Soga T, et al.
Elife
. 2021 Apr;
10.
PMID: 33902813
Oncogenes often promote cell death as well as proliferation. How oncogenes drive these diametrically opposed phenomena remains to be solved. A key question is whether cell death occurs as a...
10.
Sasaki A, Nishimura T, Takano T, Naito S, Yoo S
Nat Metab
. 2021 Apr;
3(4):546-557.
PMID: 33820991
Tissue integrity is contingent on maintaining stem cells. Intestinal stem cells (ISCs) over-proliferate during ageing, leading to tissue dysplasia in Drosophila melanogaster. Here we describe a role for white, encoding...