S Whitebread
Overview
Explore the profile of S Whitebread including associated specialties, affiliations and a list of published articles.
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Articles
37
Citations
534
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Recent Articles
1.
Traebert M, Riediger T, Whitebread S, Scharrer E, Schmid H
J Neuroendocrinol
. 2002 Jul;
14(7):580-6.
PMID: 12121496
Leptin decreases food intake and increases energy expenditure in rodents by inhibiting neurones in the hypothalamic arcuate nucleus. The growth hormone secretagogue (GHS) ghrelin is known to stimulate food intake...
2.
Rueeger H, Rigollier P, Yamaguchi Y, Schmidlin T, Schilling W, Criscione L, et al.
Bioorg Med Chem Lett
. 2000 Jun;
10(11):1175-9.
PMID: 10866375
The design of a novel series of NPY-Y5 receptor antagonists is described. Key elements for the design were the identification of weak Y5 hits from a Y1 program, results from...
3.
Brunner L, Whitebread S, Leconte I, Stricker-Krongrad A, Cumin F, Chiesi M, et al.
Int J Obes Relat Metab Disord
. 1999 Jun;
23(5):463-9.
PMID: 10375048
Objective: The purpose of the present study was to investigate the continuing validity of the hypothesis that leptin is a physiologically important regulator of food intake, using the human leptin...
4.
Clair M, Krombach R, HENDRICK J, Houck W, Hebbar L, Kribbs S, et al.
J Card Fail
. 1999 Jan;
4(4):311-23.
PMID: 9924853
Background: AT1 angiotensin II (AT1 Ang II) receptor activation has been shown to cause increased vascular resistance in the systemic (SVR), pulmonary (PVR), and coronary vasculature which may be of...
5.
Criscione L, Rigollier P, Rueger H, Stricker-Krongrad A, Wyss P, Brunner L, et al.
J Clin Invest
. 1998 Dec;
102(12):2136-45.
PMID: 9854049
The new neuropeptide Y (NPY) Y5 receptor antagonist CGP 71683A displayed high affinity for the cloned rat NPY Y5 subtype, but > 1, 000-fold lower affinity for the cloned rat...
6.
Schaffhauser A, Whitebread S, Haener R, Hofbauer K, Stricker-Krongrad A
Regul Pept
. 1998 Nov;
75-76:417-23.
PMID: 9802438
In the literature, conflicting data on the effect of NPY Y1 antisense oligodeoxynucleotides (ODNs) on food intake have been reported, describing either an increase or a decrease in feeding in...
7.
Wyss P, Stricker-Krongrad A, Brunner L, Miller J, Crossthwaite A, Whitebread S, et al.
Regul Pept
. 1998 Nov;
75-76:363-71.
PMID: 9802430
Thirteen neuropeptide Y (NPY) agonists were administered intracerebroventricularly (i.c.v.) in rats (full dose-response curves) to estimate their half-effective dose (ED50) on feeding. These values were compared to their binding affinities...
8.
Krombach R, Clair M, HENDRICK J, Houck W, Zellner J, Kribbs S, et al.
Cardiovasc Res
. 1998 Sep;
38(3):631-45.
PMID: 9747431
Background: AT1 receptor activation has been demonstrated to cause increased vascular resistance properties which may be of particular importance in the setting of congestive heart failure (CHF). The overall goal...
9.
Brunner L, Nick H, Cumin F, Chiesi M, Baum H, Whitebread S, et al.
Int J Obes Relat Metab Disord
. 1998 Jan;
21(12):1152-60.
PMID: 9426383
Objective: These studies were designed to test the hypothesis that endogenous leptin, acting within the brain plays a physiologically important role in the control of food intake in lean rats....
10.
Schaffhauser A, Stricker-Krongrad A, Brunner L, Cumin F, Gerald C, Whitebread S, et al.
Diabetes
. 1997 Nov;
46(11):1792-8.
PMID: 9356028
The recently discovered rat neuropeptide Y (NPY) receptor, the Y5 subtype, has been proposed to mediate the NPY-induced feeding response and therefore plays a central role in the regulation of...