S P Squinto
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Explore the profile of S P Squinto including associated specialties, affiliations and a list of published articles.
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56
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1592
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Recent Articles
11.
McKenzie I, Osman N, Cohney S, Vaughan H, Patton K, Mouhtouris E, et al.
Transplant Proc
. 1996 Apr;
28(2):537.
PMID: 8623253
No abstract available.
12.
Rollins S, Birks C, Setter E, Squinto S, Rother R
Hum Gene Ther
. 1996 Mar;
7(5):619-26.
PMID: 8845387
The introduction of retroviral vector producer cells (VPC) into tumors as a means of increasing transduction efficiency has recently been employed in human gene therapy trials. However, the fate of...
13.
Kroshus T, Rollins S, Dalmasso A, Elliott E, Matis L, Squinto S, et al.
Transplantation
. 1995 Dec;
60(11):1194-202.
PMID: 8525509
Prevention of hyperacute xenograft rejection in the pig-to-primate combination has been accomplished by removal of natural antibodies, complement depletion with cobra venom factor, or prevention of C3 activation with the...
14.
Sandrin M, Fodor W, Mouhtouris E, Osman N, Cohney S, Rollins S, et al.
Nat Med
. 1995 Dec;
1(12):1261-7.
PMID: 7489406
The major obstacle to successful discordant xenotransplantation is the phenomenon of hyperacute rejection (HAR). In the pig-to-primate discordant transplant setting, HAR results from the deposition of high-titre anti-alpha-galactosyl antibodies and...
15.
Evans M, Rollins S, Wolff D, Rother R, Norin A, Therrien D, et al.
Mol Immunol
. 1995 Nov;
32(16):1183-95.
PMID: 8559143
Complement activation has been implicated in the pathogenesis of several human diseases. Recently, a monoclonal antibody, (N19-8) that recognizes the human complement protein C5 has been shown to effectively block...
16.
Rother R, Fodor W, Springhorn J, Birks C, Setter E, Sandrin M, et al.
J Exp Med
. 1995 Nov;
182(5):1345-55.
PMID: 7595205
Type C retroviruses endogenous to various nonprimate species can infect human cells in vitro, yet the transmission of these viruses to humans is restricted. This has been attributed to direct...
17.
Fodor W, Rollins S, Guilmette E, Setter E, Squinto S
J Immunol
. 1995 Nov;
155(9):4135-8.
PMID: 7594566
Human cells express cell surface complement regulatory molecules that inhibit the activity of the C3/C5 convertases (DAF, MCP, CR1) or inhibit the membrane attack complex (CD59). A single molecule that...
18.
Rinder C, Rinder H, Smith B, Fitch J, Smith M, Tracey J, et al.
J Clin Invest
. 1995 Sep;
96(3):1564-72.
PMID: 7657827
Complement activation contributes to the systemic inflammatory response induced by cardiopulmonary bypass. At the cellular level, cardiopulmonary bypass activates leukocytes and platelets; however the contribution of early (3a) versus late...
19.
Evans M, Hartman S, Wolff D, Rollins S, Squinto S
J Immunol Methods
. 1995 Jul;
184(1):123-38.
PMID: 7622864
Inhibition of complement system activation requires the development of soluble nonimmunogenic inhibitors with good tissue penetrating abilities that are themselves unable to activate complement. Chimeric mouse/human Fabs capable of blocking...
20.
Springhorn J, Madri J, Squinto S
In Vitro Cell Dev Biol Anim
. 1995 Jun;
31(6):473-81.
PMID: 8589892
We have developed a novel isolation technique for harvesting human capillary endothelial cells. We compared the use of either Ulex Europaeus Agglutinin (UEA) lectin or anti-platelet endothelial cell adhesion molecule...