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S N Iyer

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Articles 42
Citations 738
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Recent Articles
1.
Ferrari M, MacDonald K, Sabetti J, Cowan T, Iyer S
Front Psychiatry . 2024 Oct; 15:1429135. PMID: 39421063
Background: Early intervention services (EIS) for psychosis have proven highly effective in treating first episode psychosis. Yet, retention or "engagement" in EIS remains highly variable. Dis/engagement as a contested concept...
2.
Halsall T, Manion I, Henderson J, Robeson P, Purcell R, Liversidge P, et al.
Health Res Policy Syst . 2020 Mar; 18(1):29. PMID: 32131848
Background: Systems transformation for health promotion, involving engagement from multiple disciplines and levels of influence, requires an investment in partnership development. Integrated youth service is a collaborative model that brings...
3.
Iyer S, Boksa P, Lal S, Shah J, Marandola G, Jordan G, et al.
Ir J Psychol Med . 2019 Nov; 32(1):51-60. PMID: 31715701
In most mental illnesses, onset occurs before the age of 25 and the earliest stages are critical. The youth bear a large share of the burden of disease associated with...
4.
Daneault J, Maraj A, Lepage M, Malla A, Schmitz N, Iyer S, et al.
Acta Psychiatr Scand . 2019 Feb; 139(4):336-347. PMID: 30712261
Objective: The experience of pre-onset subthreshold psychotic symptoms (STPS, signifying a clinical high-risk state) in first episode psychosis (FEP) predicts poorer outcomes during treatment, possibly through differential adherence to medication....
5.
Iyer S, Boekestyn L, Cassidy C, King S, Joober R, Malla A
Psychol Med . 2008 Mar; 38(8):1147-56. PMID: 18366823
Background: Few studies have examined the underlying factor structure of signs and symptoms occurring before the first psychotic episode. Our objective was to determine whether factors derived from early signs...
6.
Iyer S, Averill D, Chappell M, Yamada K, Allred A, Ferrario C
Hypertension . 2000 Sep; 36(3):417-22. PMID: 10988275
We exposed 63 adult spontaneously hypertensive rats (SHR) and 10 (mRen-2)27 transgenic hypertensive rats to a 12-day regimen of either a normal diet (0.5%) or a low-salt diet (0.05%) to...
7.
Iyer S, Hyde D, Giri S
Inflammation . 2000 Aug; 24(5):477-91. PMID: 10921510
We have previously reported the antifibrotic effects of pirfenidone (PD) in the bleomycin (BL)-hamster model of lung fibrosis. Since the development of fibrosis is generally preceded by acute lung inflammation,...
8.
Iyer S, Yamada K, Diz D, Ferrario C, Chappell M
J Cardiovasc Pharmacol . 2000 Jul; 36(1):109-17. PMID: 10892668
Prostaglandins are known to participate in the antihypertensive actions of angiotensin-converting enzyme (ACE) inhibition and angiotensin type 1 (AT1)-receptor antagonism. Because angiotensin-(1-7) [Ang-(1-7)] is markedly elevated after prolonged ACE-inhibitor treatment,...
9.
Iyer S, Gurujeyalakshmi G, Giri S
J Pharmacol Exp Ther . 1999 Sep; 291(1):367-73. PMID: 10490926
This study was undertaken to investigate whether treatment with the antifibrotic drug pirfenidone (PD) down-regulates the bleomycin (BL)-induced overexpression of transforming growth factor (TGF)-beta gene in the lungs. Hamsters were...
10.
Yamada K, Iyer S, Chappell M, Brosnihan K, Fukuhara M, Ferrario C
Regul Pept . 1999 May; 80(1-2):57-66. PMID: 10235635
Urinary excretion rates of angiotensin I (Ang I), angiotensin II (Ang II), and angiotensin-(1-7) [Ang-(1-7)] were determined in normotensive Sprague Dawley (SD), spontaneously hypertensive (SHR), and mRen-2 transgenic hypertensive animals...