S N Giri
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Explore the profile of S N Giri including associated specialties, affiliations and a list of published articles.
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Articles
206
Citations
1489
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Recent Articles
1.
Grattendick K, Nakashima J, Feng L, Giri S, Margolin S
Int Immunopharmacol
. 2008 Apr;
8(5):679-87.
PMID: 18387510
Tumor necrosis factor-alpha (TNF-alpha) is a vital component of the inflammatory process and its aberrant over-expression has been linked to numerous disease states. New treatment strategies have sought to reduce...
2.
Pesce E, Struma E, Giri S, Margolin S
Res Commun Mol Pathol Pharmacol
. 2007 Jun;
115-116:39-48.
PMID: 17564304
The antirheumatic effect of pirfenidone was compared with a positive control drug, oxyphenbutazone which is used in patients suffering from rheumatoid arthritis, in a double blind clinical trial in humans....
3.
Bruss M, Margolin S, Giri S
J Vet Pharmacol Ther
. 2004 Oct;
27(5):361-7.
PMID: 15500575
Pirfenidone, a promising antifibrotic agent, was administered orally to dogs at 0, 40, 140, and 400 mg/kg/day. Serum was collected for pirfenidone assay at 0, 26 and 39 weeks of...
4.
Giri S, Leonard S, Shi X, Margolin S, Vallyathan V
J Environ Pathol Toxicol Oncol
. 2004 Jul;
18(3):169-77.
PMID: 15281229
Pirfenidone is a newly developed antifibrotic drug that has been reported to retard the progression of pulmonary fibrosis induced by bleomycin and cyclophosphamide in animal models of lung fibrosis. The...
5.
Giri S, Biring I, Nguyen T, Wang Q, Hyde D
Nitric Oxide
. 2002 Sep;
7(2):109-18.
PMID: 12223180
The effects of aminoguanidine (AG), a specific inhibitor of inducible nitric oxide synthase, on the bleomycin (BL)-induced lung fibrosis was evaluated in mice. The animals were placed into five groups:...
6.
Giri S, Gurujeyalakshmi G, Wang Y
Adv Exp Med Biol
. 2002 Jan;
483:545-61.
PMID: 11787640
No abstract available.
7.
Wang Q, Wang Y, Hyde D, Gotwals P, Lobb R, Ryan S, et al.
Biochem Pharmacol
. 2000 Dec;
60(12):1949-58.
PMID: 11108812
Integrins are a family of transmembrane glycoproteins that can interact with components of the extracellular matrix. The alpha4beta1 and alpha4beta7 integrins are heterodimeric leukocyte cell surface molecules critical to their...
8.
Gurujeyalakshmi G, Wang Y, Giri S
Nitric Oxide
. 2000 Aug;
4(4):399-411.
PMID: 10944425
The effects of taurine (T) and niacin (N) on the influx of inflammatory cells and nitric oxide (NO) levels in bronchoalveolar lavage fluid (BALF) and expression of inducible NO synthase...
9.
Iyer S, Hyde D, Giri S
Inflammation
. 2000 Aug;
24(5):477-91.
PMID: 10921510
We have previously reported the antifibrotic effects of pirfenidone (PD) in the bleomycin (BL)-hamster model of lung fibrosis. Since the development of fibrosis is generally preceded by acute lung inflammation,...
10.
Wild J, Giri S, MOORE R, Pessah I
Arch Biochem Biophys
. 2000 Jun;
379(1):109-18.
PMID: 10864448
The ryanodine-sensitive calcium channels, also called ryanodine receptors, are intracellular Ca(2+)-release channels that have been shown to bind the neutral plant alkaloid ryanodine with nanomolar affinity. The activity of the...