S J Nishio
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Explore the profile of S J Nishio including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
280
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Recent Articles
1.
Plopper C, Joad J, Miller L, Schelegle E, Fanucchi M, Van Winkle L, et al.
Clin Exp Allergy
. 2012 Jun;
42(7):1104-18.
PMID: 22702509
Background: The risks for infants and young children receiving inhaled corticosteroid (ICS) therapy are largely unknown. Recent clinical studies indicate that ICS therapy in pre-school children with symptoms of asthma...
2.
Evans M, Fanucchi M, BAKER G, Van Winkle L, Pantle L, Nishio S, et al.
Clin Exp Allergy
. 2004 Jul;
34(7):1131-6.
PMID: 15248862
Background: In previous studies, we showed that repeated exposure to (1) house dust mite allergen (HDMA) (Dermatophagoides farinae) caused thickening of the basement membrane zone (BMZ) and (2) HDMA+ozone (O3)...
3.
Plopper C, Van Winkle L, Fanucchi M, Malburg S, Nishio S, Chang A, et al.
Am J Respir Cell Mol Biol
. 2001 Mar;
24(3):272-81.
PMID: 11245626
One of the presumed roles of intracellular glutathione (GSH) is the protection of cells from injury by reactive intermediates produced by the metabolism of xenobiotics. To establish whether GSH depletion...
4.
Van Winkle L, Johnson Z, Nishio S, Brown C, Plopper C
Am J Respir Cell Mol Biol
. 1999 Jul;
21(1):44-53.
PMID: 10385592
Naphthalene causes severe dose- and site-selective injury to mouse nonciliated bronchiolar (Clara) epithelial cells. Toxicity is characterized by exfoliation of injured Clara cells into the airway lumen 24 h after...
5.
Smiley-Jewell S, Nishio S, Weir A, Plopper C
Am J Physiol
. 1998 May;
274(4):L485-98.
PMID: 9575866
Nonciliated bronchiolar (Clara) cells metabolize environmental toxicants, are progenitor cells during development, and differentiate postnatally. Because differentiating Clara cells of neonatal rabbits are injured at lower doses by the cytochrome...
6.
Cellular response in naphthalene-induced Clara cell injury and bronchiolar epithelial repair in mice
Van Winkle L, Buckpitt A, Nishio S, Isaac J, Plopper C
Am J Physiol
. 1995 Dec;
269(6 Pt 1):L800-18.
PMID: 8572242
Clara cells, progenitors for bronchiolar epithelium, are also primary targets for metabolically activated pulmonary cytotoxicants and have an abundance of the cytochrome P-450 monooxygenases required for xenobiotic metabolism. To define...
7.
Edwards L, Read L, Nishio S, Weir A, Hull W, Barry S, et al.
J Pharmacol Exp Ther
. 1995 Aug;
274(2):1025-32.
PMID: 7636717
To compare the effects of epidermal growth factor (EGF) and betamethasone on the morphogenesis of the gas exchange region and the differentiation of the alveolar type II cell during fetal...
8.
Plopper C, Weir A, Nishio S, Chang A, VOIT M, Philpot R, et al.
J Pharmacol Exp Ther
. 1994 May;
269(2):867-80.
PMID: 8182556
The bronchiolar Clara cell is one of the primary targets in adult mammals for environmental contaminants metabolized by cytochrome P450 (CYP) monooxygenases. Previous studies show that the onset of CYP...
9.
Plopper C, Nishio S, Alley J, Kass P, Hyde D
Am J Respir Cell Mol Biol
. 1992 Dec;
7(6):606-13.
PMID: 1449808
Although it is well established that the nonciliated bronchiolar epithelial (Clara) cell serves as the progenitor for itself and ciliated cells in the adult lung following bronchiolar epithelial injury, the...
10.
Plopper C, Macklin J, Nishio S, Hyde D, Buckpitt A
Lab Invest
. 1992 Nov;
67(5):553-65.
PMID: 1434534
Background: The purpose of this study was to define, in quantitative terms, epithelial alterations produced by the cytochrome P-450-activated Clara cell cytotoxicant, naphthalene, in lobar bronchi and terminal bronchioles of...