C G Plopper
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Explore the profile of C G Plopper including associated specialties, affiliations and a list of published articles.
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182
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2137
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Recent Articles
1.
Plopper C, Joad J, Miller L, Schelegle E, Fanucchi M, Van Winkle L, et al.
Clin Exp Allergy
. 2012 Jun;
42(7):1104-18.
PMID: 22702509
Background: The risks for infants and young children receiving inhaled corticosteroid (ICS) therapy are largely unknown. Recent clinical studies indicate that ICS therapy in pre-school children with symptoms of asthma...
2.
Plopper C, Mango G, Hatch G, Wong V, Toskala E, Reynolds S, et al.
Toxicol Appl Pharmacol
. 2005 Oct;
213(1):74-85.
PMID: 16226776
Increases in Clara cell abundance or cellular expression of Clara cell secretory protein (CCSP) may cause increased tolerance of the lung to acute oxidant injury by repeated exposure to ozone...
3.
Miller L, Hurst S, Coffman R, Tyler N, Stovall M, Chou D, et al.
Clin Exp Allergy
. 2005 Jul;
35(7):894-906.
PMID: 16008676
Background: Accumulation of immune cell populations and their cytokine products within tracheobronchial airways contributes to the pathogenesis of allergic asthma. It has been postulated that peripheral regions of the lung...
4.
Phimister A, Nagasawa H, Buckpitt A, Plopper C
J Biochem Mol Toxicol
. 2005 Mar;
19(1):42-51.
PMID: 15736154
Naphthalene is metabolized in the lung and liver to reactive intermediates by cytochrome P450 enzymes. These reactive species deplete glutathione, covalently bind to proteins, and cause necrosis in Clara cells...
5.
Tran M, Weir A, Fanucchi M, Rodriguez A, Pantle L, Smiley-Jewell S, et al.
Clin Exp Allergy
. 2004 Oct;
34(10):1627-33.
PMID: 15479280
Background: Airway smooth muscle hypertrophy is closely associated with the pathophysiology of hyper-reactive airways in allergic asthma. Objective: To determine whether repeated exposure to allergens during postnatal lung development promotes...
6.
Phimister A, Lee M, Morin D, Buckpitt A, Plopper C
Toxicol Sci
. 2004 Aug;
82(1):268-78.
PMID: 15319489
Naphthalene (NA) is metabolized to highly reactive intermediates that are primarily detoxified by conjugation to glutathione (GSH). Intraperitoneal administration of naphthalene causes substantial loss of both hepatic and respiratory GSH,...
7.
Evans M, Fanucchi M, BAKER G, Van Winkle L, Pantle L, Nishio S, et al.
Clin Exp Allergy
. 2004 Jul;
34(7):1131-6.
PMID: 15248862
Background: In previous studies, we showed that repeated exposure to (1) house dust mite allergen (HDMA) (Dermatophagoides farinae) caused thickening of the basement membrane zone (BMZ) and (2) HDMA+ozone (O3)...
8.
Miller L, Plopper C, Hyde D, Gerriets J, Pieczarka E, Tyler N, et al.
Clin Exp Allergy
. 2003 Dec;
33(12):1686-94.
PMID: 14656356
Background: The effect of chronic environmental aeroallergen exposure on the immune system and airways has not been experimentally defined in very young children. Objective: The purpose of this study was...
9.
Kips J, Anderson G, Fredberg J, Herz U, Inman M, Jordana M, et al.
Eur Respir J
. 2003 Sep;
22(2):374-82.
PMID: 12952276
In vivo animal models can offer valuable information on several aspects of asthma pathogenesis and treatment. The mouse is increasingly used in these models, mainly because this species allows for...
10.
Smiley-Jewell S, Tran M, Weir A, Johnson Z, Van Winkle L, Plopper C
J Appl Physiol (1985)
. 2002 Sep;
93(4):1506-14.
PMID: 12235053
Airway smooth muscle remodeling is implicated in a number of constrictive pulmonary diseases such as asthma and may include changes in smooth muscle orientation and abundance. Both factors were compared...