S E Brenner
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Explore the profile of S E Brenner including associated specialties, affiliations and a list of published articles.
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28
Citations
4968
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Recent Articles
1.
Chhibber A, French C, Yee S, Gamazon E, Theusch E, Qin X, et al.
Pharmacogenomics J
. 2016 Feb;
17(2):137-145.
PMID: 26856248
Variation in the expression level and activity of genes involved in drug disposition and action ('pharmacogenes') can affect drug response and toxicity, especially when in tissues of pharmacological importance. Previous...
2.
Carninci P, Kasukawa T, Katayama S, Gough J, Frith M, Maeda N, et al.
Science
. 2005 Sep;
309(5740):1559-63.
PMID: 16141072
This study describes comprehensive polling of transcription start and termination sites and analysis of previously unidentified full-length complementary DNAs derived from the mouse genome. We identify the 5' and 3'...
3.
Zupicich J, Brenner S, Skarnes W
Genome Biol
. 2002 Jan;
2(12):RESEARCH0050.
PMID: 11790253
Background: Sequestration of transcription factors in the membrane is emerging as an important mechanism for the regulation of gene expression. A handful of membrane-spanning transcription factors has been previously identified...
4.
Brenner S
Nat Rev Genet
. 2001 Oct;
2(10):801-9.
PMID: 11584296
Structural genomics projects aim to provide an experimental or computational three-dimensional model structure for all of the tractable macromolecules that are encoded by complete genomes. To this end, pilot centres...
5.
Brenner S
Nat Struct Biol
. 2000 Dec;
7 Suppl:967-9.
PMID: 11104002
Structural genomics aims to use high-throughput structure determination and computational analysis to provide three-dimensional models of every tractable protein. The process of choosing proteins for experimental structure characterization is known...
6.
Brenner S, Levitt M
Protein Sci
. 2000 Mar;
9(1):197-200.
PMID: 10739263
Structural genomics projects aim to provide an experimental structure or a good model for every protein in all completed genomes. Most of the experimental work for these projects will be...
7.
Lo Conte L, Ailey B, Hubbard T, Brenner S, Murzin A, Chothia C
Nucleic Acids Res
. 1999 Dec;
28(1):257-9.
PMID: 10592240
The Structural Classification of Proteins (SCOP) database provides a detailed and comprehensive description of the relationships of known protein structures. The classification is on hierarchical levels: the first two levels,...
8.
Brenner S, Koehl P, Levitt M
Nucleic Acids Res
. 1999 Dec;
28(1):254-6.
PMID: 10592239
The ASTRAL compendium provides several databases and tools to aid in the analysis of protein structures, particularly through the use of their sequences. The SPACI scores included in the system...
9.
10.
Hubbard T, Ailey B, Brenner S, Murzin A, Chothia C
Acta Crystallogr D Biol Crystallogr
. 1999 Mar;
54(Pt 6 Pt 1):1147-54.
PMID: 10089491
The Structural Classification of Proteins (SCOP) database provides a detailed and comprehensive description of the relationships of all known protein structures. The classification is on hierarchical levels: the first two...