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T Hubbard

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Articles 41
Citations 12514
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Recent Articles
1.
Hubbard T, Beaton C
Ann R Coll Surg Engl . 2017 Oct; 100(4):346-347. PMID: 29022821
No abstract available.
2.
Wilming L, Gilbert J, Howe K, Trevanion S, Hubbard T, Harrow J
Nucleic Acids Res . 2007 Nov; 36(Database issue):D753-60. PMID: 18003653
The Vertebrate Genome Annotation (Vega) database (http://vega.sanger.ac.uk) was first made public in 2004 and has been designed to view manual annotation of human, mouse and zebrafish genomic sequences produced at...
3.
Gregory S, Barlow K, McLay K, Kaul R, Swarbreck D, Dunham A, et al.
Nature . 2006 May; 441(7091):315-21. PMID: 16710414
The reference sequence for each human chromosome provides the framework for understanding genome function, variation and evolution. Here we report the finished sequence and biological annotation of human chromosome 1....
4.
Ashurst J, Chen C, Gilbert J, Jekosch K, Keenan S, Meidl P, et al.
Nucleic Acids Res . 2004 Dec; 33(Database issue):D459-65. PMID: 15608237
The Vertebrate Genome Annotation (Vega) database (http://vega.sanger.ac.uk) has been designed to be a community resource for browsing manual annotation of finished sequences from a variety of vertebrate genomes. Its core...
5.
Hubbard T, Andrews D, Caccamo M, Cameron G, Chen Y, Clamp M, et al.
Nucleic Acids Res . 2004 Dec; 33(Database issue):D447-53. PMID: 15608235
The Ensembl (http://www.ensembl.org/) project provides a comprehensive and integrated source of annotation of large genome sequences. Over the last year the number of genomes available from the Ensembl site has...
6.
Deloukas P, Earthrowl M, Grafham D, Rubenfield M, French L, Steward C, et al.
Nature . 2004 May; 429(6990):375-81. PMID: 15164054
The finished sequence of human chromosome 10 comprises a total of 131,666,441 base pairs. It represents 99.4% of the euchromatic DNA and includes one megabase of heterochromatic sequence within the...
7.
Humphray S, Oliver K, HUNT A, Plumb R, Loveland J, Howe K, et al.
Nature . 2004 May; 429(6990):369-74. PMID: 15164053
Chromosome 9 is highly structurally polymorphic. It contains the largest autosomal block of heterochromatin, which is heteromorphic in 6-8% of humans, whereas pericentric inversions occur in more than 1% of...
8.
Dunham A, MATTHEWS L, Burton J, Ashurst J, Howe K, Ashcroft K, et al.
Nature . 2004 Apr; 428(6982):522-8. PMID: 15057823
Chromosome 13 is the largest acrocentric human chromosome. It carries genes involved in cancer including the breast cancer type 2 (BRCA2) and retinoblastoma (RB1) genes, is frequently rearranged in B-cell...
9.
Birney E, Andrews D, Bevan P, Caccamo M, Cameron G, Chen Y, et al.
Nucleic Acids Res . 2003 Dec; 32(Database issue):D468-70. PMID: 14681459
The Ensembl (http://www.ensembl.org/) database project provides a bioinformatics framework to organize biology around the sequences of large genomes. It is a comprehensive and integrated source of annotation of large genome...
10.
Mungall A, Palmer S, Sims S, Edwards C, Ashurst J, Wilming L, et al.
Nature . 2003 Oct; 425(6960):805-11. PMID: 14574404
Chromosome 6 is a metacentric chromosome that constitutes about 6% of the human genome. The finished sequence comprises 166,880,988 base pairs, representing the largest chromosome sequenced so far. The entire...