S Dreikorn
Overview
Explore the profile of S Dreikorn including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
274
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Recent Articles
1.
Vicente M, Cabello A, Platas G, Basilio A, Diez M, Dreikorn S, et al.
J Appl Microbiol
. 2001 Nov;
91(5):806-13.
PMID: 11722657
Aims: Natural fungal products were screened for antifungal compounds. The mode of action of one of the hits found and the taxonomy of the producing organism were analysed. Methods And...
2.
Onishi J, Meinz M, Thompson J, Curotto J, Dreikorn S, Rosenbach M, et al.
Antimicrob Agents Chemother
. 2000 Jan;
44(2):368-77.
PMID: 10639364
The increasing incidence of life-threatening fungal infections has driven the search for new, broad-spectrum fungicidal agents that can be used for treatment and prophylaxis in immunocompromised patients. Natural-product inhibitors of...
3.
Mandala S, Thornton R, Milligan J, Rosenbach M, Garcia-Calvo M, Bull H, et al.
J Biol Chem
. 1998 Jun;
273(24):14942-9.
PMID: 9614099
Rustmicin is a 14-membered macrolide previously identified as an inhibitor of plant pathogenic fungi by a mechanism that was not defined. We discovered that rustmicin inhibits inositol phosphoceramide synthase, resulting...
4.
Mandala S, Thornton R, Frommer B, Dreikorn S, KURTZ M
J Antibiot (Tokyo)
. 1997 Apr;
50(4):339-43.
PMID: 9186561
Viridiofungins are broad spectrum antifungal agents that inhibit the squalene synthase in vitro, but do not specifically inhibit fungal ergosterol synthesis in whole cells, indicating a different mode of action...
5.
KURTZ M, Douglas C, Marrinan J, Nollstadt K, Onishi J, Dreikorn S, et al.
Antimicrob Agents Chemother
. 1994 Dec;
38(12):2750-7.
PMID: 7695257
The pneumocandins are natural lipopeptide products of the echinocandin class which inhibit the synthesis of 1,3-beta-D-glucan in susceptible fungi. The lack of a corresponding pathway in mammalian hosts makes this...
6.
KURTZ M, Heath I, Marrinan J, Dreikorn S, Onishi J, Douglas C
Antimicrob Agents Chemother
. 1994 Jul;
38(7):1480-9.
PMID: 7979276
The lipopeptide antifungal agents, echinocandins, papulacandins, and pneumocandins, kill Candida albicans by inhibiting glucan synthesis. For this fungus, there is a good correlation of in vitro enzyme inhibition with in...