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S Dijols

Explore the profile of S Dijols including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 14
Citations 91
Followers 0
Related Specialties
Biochemistry
Chemistry
General Medicine
Top 10 Co-Authors
D Mansuy
P M Dansette
N T Ha-Duong
C Minoletti
J L Boucher
A Mancy
D J Stuehr
A C Macherey
I Artaud
S Poli
Published In
Biochemistry
J Med Chem
Chem Res Toxicol
Eur J Biochem
Arch Biochem Biophys
Affiliations
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Recent Articles
1.
Reduction of nilutamide by NO synthases: implications for the adverse effects of this nitroaromatic antiandrogen drug
Ask K, Dijols S, Giroud C, Casse L, Frapart Y, Sari M, et al.
Chem Res Toxicol . 2003 Dec; 16(12):1547-54. PMID: 14680368
Nitric oxide synthases (NOSs) are flavohemeproteins that catalyze the oxidation of l-arginine to l-citrulline with formation of the widespread signal molecule NO. Beside their fundamental role in NO biosynthesis, these...
2.
Inhibition by ticlopidine and its derivatives of human liver cytochrome p450. Mechanism-based inactivation of CYP 2C19 by ticlopidine
Ha-Duong N, Dijols S, Macherey A, Dansette P, Mansuy D
Adv Exp Med Biol . 2002 Jan; 500:145-8. PMID: 11764927
No abstract available.
3.
Synthesis of sulfaphenazole derivatives and their use as inhibitors and tools for comparing the active sites of human liver cytochromes P450 of the 2C subfamily
Ha-Duong N, Dijols S, Minoletti C, Dansette P, Mansuy D
J Med Chem . 2001 Oct; 44(22):3622-31. PMID: 11606127
Twenty-three new derivatives of sulfaphenazole (SPA) were synthesized to further explore the topology of the active sites of human liver cytochromes P450 of the 2C subfamily and to find new...
4.
Interaction of new sulfaphenazole derivatives with human liver cytochrome p450 2Cs: structural determinants required for selective recognition by CYP 2C9 and for inhibition of human CYP 2Cs
Ha-Duong N, Dijols S, Sari M, Dansette P, Mansuy D
Arch Biochem Biophys . 2001 Oct; 394(2):189-200. PMID: 11594733
A series of new derivatives of sulfaphenazole (SPA), in which the NH(2) and phenyl substituents of SPA are replaced by various groups or in which the sulfonamide function of SPA...
5.
Ticlopidine as a selective mechanism-based inhibitor of human cytochrome P450 2C19
Ha-Duong N, Dijols S, Macherey A, Goldstein J, Dansette P, Mansuy D
Biochemistry . 2001 Oct; 40(40):12112-22. PMID: 11580286
Experiments using recombinant yeast-expressed human liver cytochromes P450 confirmed previous literature data indicating that ticlopidine is an inhibitor of CYP 2C19. The present studies demonstrated that ticlopidine is selective for...
6.
Oxidation of N(omega)-hydroxyarginine analogues by NO-synthase: the simple, non amino acid N-butyl N'-hydroxyguanidine is almost as efficient an NO precursor as N(omega)-hydroxyarginine
Dijols S, Perollier C, Pethe S, Attias R, Boucher J, Stuehr D, et al.
J Med Chem . 2001 Sep; 44(20):3199-202. PMID: 11563918
No abstract available.
7.
N-hydroxyguanidines as new heme ligands: UV-visible, EPR, and resonance Raman studies of the interaction of various compounds bearing a C=NOH function with microperoxidase-8
Dijols S, Boucher J, Mahy J, Ricoux R, Desbois A, Zimmermann J, et al.
Biochemistry . 2001 Aug; 40(33):9909-17. PMID: 11502185
Interaction between microperoxidase-8 (MP8), a water-soluble hemeprotein model, and a wide range of N-aryl and N-alkyl N'-hydroxyguanidines and related compounds has been investigated using UV-visible, EPR, and resonance Raman spectroscopies....
8.
Toward model complexes of Co-containing nitrile hydratases: synthesis, complete characterization and reactivity toward ligands such as CN- and NO of the first square planar CoIII complex with two different carboxamido nitrogens and two thiolato...
Chatel S, Rat M, Dijols S, Leduc P, Tuchagues J, Mansuy D, et al.
J Inorg Biochem . 2000 Sep; 80(3-4):239-46. PMID: 11001095
A [CoIII(N2S2)]NEt4 complex, with two carboxamido nitrogens and two alkylthiolato sulfurs, was prepared from N,N'-(2-thioacetylisobutyryl)-2-aminobenzylamine, and characterized. It crystallizes with a distorted square planar structure including two short Co-N bonds...
9.
Diclofenac and its derivatives as tools for studying human cytochromes P450 active sites: particular efficiency and regioselectivity of P450 2Cs
Mancy A, Antignac M, Minoletti C, Dijols S, Mouries V, Duong N, et al.
Biochemistry . 1999 Nov; 38(43):14264-70. PMID: 10572000
A comparison of the oxidations of diclofenac with microsomes of yeasts expressing various human liver cytochromes P450 showed that P450 2C9 regioselectively led to 4'-hydroxy diclofenac (4'-OHD) whereas P450 3A4...
10.
Comparison of the substrate specificities of human liver cytochrome P450s 2C9 and 2C18: application to the design of a specific substrate of CYP 2C18
Minoletti C, Dijols S, Dansette P, Mansuy D
Biochemistry . 1999 Jul; 38(24):7828-36. PMID: 10387023
A series of 2-aroylthiophenes derived from tienilic acid by replacement of its OCH2COOH substituent with groups bearing various functions have been synthesized and studied as possible substrates of recombinant human...