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S D Spencer

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Articles 11
Citations 910
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Recent Articles
1.
Lewis J, Stephens S, Horenstein R, OConnell J, Ryan K, Peer C, et al.
J Thromb Haemost . 2013 Jul; 11(9):1640-6. PMID: 23809542
Background: Cytochrome P450 2C19 (CYP2C19) is the principal enzyme responsible for converting clopidogrel into its active metabolite, and common genetic variants have been identified, most notably CYP2C19*2 and CYP2C19*17, that...
2.
Li H, Spencer S, Lian L, Zhang Z, Lu P
Epidemiol Infect . 2011 Nov; 140(9):1607-11. PMID: 22117136
Measles control in China is monitored in part by surveillance of circulating wild-type viruses. The objective of this study was genetic characterization and phylogenetic analysis of measles strains in the...
3.
Ross S, Spencer S, Lasky L, Koeppen H
Am J Pathol . 2001 Mar; 158(3):809-16. PMID: 11238029
Prostate stem cell antigen (PSCA) is a GPI-anchored membrane protein whose expression is reportedly up-regulated in a majority of human prostate cancers, including advanced stages and metastases. In this study,...
4.
Wu Y, Spencer S, Lasky L
J Biol Chem . 1998 Apr; 273(10):5765-70. PMID: 9488710
Wiskott-Aldrich syndrome is an X-linked hematopoietic disease that manifests itself in platelet deficiency and a compromised immune system. Analysis of hematopoietic cells from affected individuals reveals that mutations in the...
5.
Spencer S, Di Marco F, Hooley J, Bauer M, Ryan A, Sordat B, et al.
J Exp Med . 1998 Mar; 187(4):571-8. PMID: 9463407
The orphan receptor CRF2-4 is a member of the class II cytokine receptor family (CRF2), which includes the interferon receptors, the interleukin (IL) 10 receptor, and tissue factor. CRFB4, the...
6.
Chen K, Nishimura M, Armanini M, Crowley C, Spencer S, PHILLIPS H
J Neurosci . 1997 Sep; 17(19):7288-96. PMID: 9295375
Administration of nerve growth factor (NGF) to aged or lesioned animals has been shown to reverse the atrophy of basal forebrain cholinergic neurons and ameliorate behavioral deficits. To examine the...
7.
Shelton D, Sutherland J, Gripp J, Camerato T, Armanini M, PHILLIPS H, et al.
J Neurosci . 1995 Jan; 15(1 Pt 2):477-91. PMID: 7823156
Using molecular cloning techniques, human homologs of the known members of the trk family of neurotrophin receptors have been cloned and sequenced. Overall, there is a high degree of similarity...
8.
Cohen J, Snow J, Spencer S, Levinson A
Proc Natl Acad Sci U S A . 1994 Oct; 91(22):10470-4. PMID: 7937977
One of the earliest events in the process of intron removal from mRNA precursors is the establishment of a base-pairing interaction between U1 small nuclear (sn) RNA and the 5'...
9.
Zeigler F, Bennett B, Jordan C, Spencer S, Baumhueter S, Carroll K, et al.
Blood . 1994 Oct; 84(8):2422-30. PMID: 7919361
The flk-2/flt-3 receptor tyrosine kinase was cloned from a hematopoietic stem cell population and is considered to play a potential role in the developmental fate of the stem cell. Using...
10.
de Sauvage F, Hass P, Spencer S, Malloy B, Gurney A, Spencer S, et al.
Nature . 1994 Jun; 369(6481):533-8. PMID: 8202154
Physiological platelet synthesis is thought to require the humoral activities of meg-CSF and thrombopoietin, which respectively promote proliferation and maturation of megakaryocytic cells. A meg-CSF/thrombopoietin-like protein that is present in...