S D Shapiro
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Explore the profile of S D Shapiro including associated specialties, affiliations and a list of published articles.
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119
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7062
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Recent Articles
1.
Zhao Y, Olonisakin T, Xiong Z, Hulver M, Sayeed S, Yu M, et al.
Mucosal Immunol
. 2014 Dec;
8(4):896-905.
PMID: 25492474
Neutrophil elastase (NE) and cathepsin G (CG) contribute to intracellular microbial killing but, if left unchecked and released extracellularly, promote tissue damage. Conversely, mechanisms that constrain neutrophil serine protease activity...
2.
Yoshida S, Minematsu N, Chubachi S, Nakamura H, Miyazaki M, Tsuduki K, et al.
Am J Physiol Lung Cell Mol Physiol
. 2012 Sep;
303(10):L852-60.
PMID: 22962014
Efferocytosis is believed to be a key regulator for lung inflammation in chronic obstructive pulmonary disease. In this study we pharmacologically inhibited efferocytosis with annexin V and attempted to determine...
3.
Shapiro S, Iannino A
IEEE Trans Pattern Anal Mach Intell
. 2011 Aug;
1(3):310-7.
PMID: 21868864
Graphical techniques are presented for estimating Hough transform performance for detecting straight lines in noisy digital pictures. The methods show explicitly the influence of noise due, for example, to quantizing...
4.
Shapiro S, Kelley D, Kobayashi D
Methods Mol Med
. 2011 Feb;
56:383-90.
PMID: 21336915
Matrix metalloproteinases (MMPs) (1,2) comprise a family of over 20 matrix degrading enzymes believed to be essential for normal development and physiologic tissue remodeling and repair. Abnormal expression of metalloproteinases...
5.
Foreman M, DeMeo D, Hersh C, Carey V, Fan V, Reilly J, et al.
Eur Respir J
. 2008 Jun;
32(4):938-44.
PMID: 18550614
Exacerbations of chronic obstructive pulmonary disease (COPD) reduce quality of life and increase mortality. Genetic variation might explain the substantial variability seen in exacerbation frequency among COPD subjects with similar...
6.
Shapiro S
Eur Respir J
. 2007 Feb;
29(2):375-8.
PMID: 17264324
Animal models play an important role in the understanding of the pathogenesis of chronic obstructive pulmonary disease (COPD). The applicability of findings to human COPD depends upon several factors, including...
7.
Ji H, Houghton A, Mariani T, Perera S, Kim C, Padera R, et al.
Oncogene
. 2005 Nov;
25(14):2105-12.
PMID: 16288213
Activating mutations in K-ras are one of the most common genetic alterations in human lung cancer. To dissect the role of K-ras activation in bronchial epithelial cells during lung tumorigenesis,...
8.
Molet S, Belleguic C, Lena H, Germain N, Bertrand C, Shapiro S, et al.
Inflamm Res
. 2005 Feb;
54(1):31-6.
PMID: 15723202
Objective And Design: Chronic obstructive pulmonary disease (COPD) is characterized by an inflammatory process and airway remodeling involving matrix metalloproteinases (MMPs). Thus, we analyzed the expression and release of MMP-12...
9.
Barnes P, Shapiro S, Pauwels R
Eur Respir J
. 2003 Oct;
22(4):672-88.
PMID: 14582923
Chronic obstructive pulmonary disease is a leading cause of death and disability, but has only recently been extensively explored from a cellular and molecular perspective. There is a chronic inflammation...
10.