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S D Kosanke

Explore the profile of S D Kosanke including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 164
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Recent Articles
1.
Yamano T, Kosanke S, Rikans L
Toxicol Appl Pharmacol . 2000 Jan; 161(3):225-30. PMID: 10620479
The influence of aging on the sensitivity of the liver to the acute toxicity of cadmium has not been studied previously in adult rats. In this study hepatotoxicity caused by...
2.
Taylor Jr F, Bryant A, Blick K, Hack E, Jansen P, Kosanke S, et al.
Clin Infect Dis . 1999 Aug; 29(1):167-77. PMID: 10433581
Group A streptococcal infections, ranging from necrotizing fasciitis and myositis to toxic shock syndrome, have increased over the last 10 years. We developed the first primate model of necrotizing fasciitis...
3.
Taylor Jr F, Tesh V, DeBault L, Li A, Chang A, Kosanke S, et al.
Am J Pathol . 1999 May; 154(4):1285-99. PMID: 10233866
The baboon response to intravenous infusion of Shiga toxin 1 (Stx-1) varied from acute renal failure, proteinuria, hyperkalemia, and melena with minimal perturbation of host inflammatory and hemostatic systems (high-dose...
4.
RANDOLPH M, White G, Kosanke S, Bild G, Carr C, GALLUPPI G, et al.
Thromb Haemost . 1998 Jun; 79(5):1048-53. PMID: 9609245
This study was designed to determine the effect of a delayed infusion (T+120 min) of alanyl tissue factor pathway inhibitor (ala-TFPI) on the response to LD100 E. coli. We hypothesized...
5.
Schaefer C, Janzen E, West M, Poyer J, Kosanke S
Free Radic Biol Med . 1996 Jan; 21(4):427-36. PMID: 8886792
For greatest efficacy, it is desirable to use spin trapping agents in the highest concentrations possible. Fifty-four male Sprague-Dawley rats were used to explore the relative toxicity of four representative...
6.
Ringer D, Howell B, NORTON T, Woulfe G, Duffel M, Kosanke S
Mol Carcinog . 1994 Jan; 9(1):2-9. PMID: 8297481
Enzymatic and immunohistochemical experiments were conducted to evaluate the mechanistic basis for the downregulation of the important detoxication/bioactivation enzyme aryl sulfotransferase IV (AST IV) during 2-acetylaminofluorene (2AAF)-induced hepatocarcinogenesis. To distinguish...
7.
Hornbrook K, Kosanke S, Rikans L
Exp Mol Pathol . 1993 Aug; 59(1):27-37. PMID: 8262163
The ability of concurrent intraperitoneal injections of endotoxin (0.1 micrograms/kg) and galactosamine (700 mg/kg) to produce liver damage was determined in fasted C57Bl/6 mice of different ages: 2 months (young),...
8.
Kiehlbauch C, Kosanke S, Ringer D
Carcinogenesis . 1993 Jul; 14(7):1435-40. PMID: 8330362
The exposure of rats to the carcinogen 2-acetylaminofluorene (2-AAF) results in the accumulation of DNA-damaging adducts. The inability of cells to repair such damage adequately is a putative causal event...
9.
Rikans L, Cai Y, Kosanke S, Venkataraman P
Drug Metab Dispos . 1993 Jul; 21(4):605-10. PMID: 8104118
The aim of this study was to determine the influence of aging on diquat-induced redox cycling in liver microsomes and diquat hepatotoxicity in rats. Diquat-stimulated production of superoxide anion radical...
10.
Hinshaw L, EMERSON Jr T, Taylor Jr F, Chang A, Duerr M, Peer G, et al.
J Trauma . 1992 Oct; 33(4):568-73. PMID: 1433404
A successful experimental treatment for gram-positive sepsis to our knowledge has not been achieved. The objectives of this study were to develop a nonhuman primate model of lethal gram-positive sepsis...