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L B Hinshaw

Explore the profile of L B Hinshaw including associated specialties, affiliations and a list of published articles. Areas
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Articles 228
Citations 1199
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Recent Articles
1.
Kinasewitz G, Chang A, Peer G, Hinshaw L, Taylor Jr F
Shock . 2000 Feb; 13(2):100-9. PMID: 10670839
The physiological, hemostatic, and immunological responses of 12 chronically instrumented conscious baboons with sepsis due to Escherichia coli peritonitis were compared with that of similarly instrumented controls. Chronic indwelling cannulae...
2.
RANDOLPH M, White G, Kosanke S, Bild G, Carr C, GALLUPPI G, et al.
Thromb Haemost . 1998 Jun; 79(5):1048-53. PMID: 9609245
This study was designed to determine the effect of a delayed infusion (T+120 min) of alanyl tissue factor pathway inhibitor (ala-TFPI) on the response to LD100 E. coli. We hypothesized...
3.
Arbuckle M, Gross T, Scofield R, Hinshaw L, Chang A, Taylor Jr F, et al.
J Investig Med . 1998 Apr; 46(2):58-65. PMID: 9549228
Background: Systemic lupus erythematosus (SLE) is characterized by humoral autoimmunity against the spliceosomal proteins, including Sm B/B'. In SLE patients with anti-Sm B/B' antibodies the proline rich sequence, PPPGMRPP, is...
4.
Hinshaw L
Crit Care Med . 1996 Jun; 24(6):1072-8. PMID: 8681576
Objective: An overview of the importance of understanding mechanisms occurring in the microcirculation during septic and endotoxic shock. The thesis of the paper is to place emphasis on this important...
5.
Jansen P, de Jong I, Hart M, Kim K, Aarden L, Hinshaw L, et al.
J Immunol . 1996 Jun; 156(11):4401-7. PMID: 8666813
Leukemia inhibitory factor (LIF), a pleiotropic cytokine with many biologic effects overlapping with those of IL-6, has been implicated in the pathogenesis of sepsis. We here analyzed the kinetics of...
6.
Li A, Chang A, Peer G, Hinshaw L, Taylor Jr F
Shock . 1996 Apr; 5(4):274-9. PMID: 8721387
The procoagulant activity of mononuclear cells (MNCs) may play an important role in the disseminated intravascular coagulation seen in septic shock. This study compares the capacity of Escherichia coli (E....
7.
Li A, Taylor Jr F, Chang A, Peer G, Dong F, Hinshaw L
Thromb Res . 1995 Aug; 79(4):395-403. PMID: 7482443
Polyethylene glycol(PEG) was used to precipitate fibrinogen to prepare defibrinated plasma in the two stage clotting assay of antithrombin activity. Five percent PEG-8000 precipitated fibrinogen from plasma without loss of...
8.
Hinshaw L, EMERSON Jr T, Chang A, Duerr M, Peer G, Fournel M
Circ Shock . 1994 Dec; 44(4):221-9. PMID: 7628065
Therapy with anti-TNF antibody is reported to be effective in preventing morbidity and mortality in baboons given lethal infusions of Escherichia coli. Treated animals survived, and organ histopathology was absent...
9.
Carr C, Bild G, Chang A, Peer G, Palmier M, Frazier R, et al.
Circ Shock . 1994 Nov; 44(3):126-37. PMID: 7600636
Excessive coagulation is a typical response to the vascular injury occurring in gram negative sepsis. This study evaluated the pharmacological effects of the use of a recombinant Escherichia coli derived...
10.
Taylor Jr F, Kosanke S, Randolph M, Emerson T, Hinshaw L, White G, et al.
Circ Shock . 1994 Feb; 42(2):92-103. PMID: 8013066
This paper is divided into a retrospective descriptive section in which we report on three distinctly different and spontaneous responses of the baboon to LD100 Eschericia coli observed over the...