S Canaan
Overview
Explore the profile of S Canaan including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
342
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Recent Articles
1.
Dedieu L, Serveau-Avesque C, Kremer L, Canaan S
Biochimie
. 2012 Jul;
95(1):66-73.
PMID: 22819994
Tuberculosis (TB) is one of the deadliest infectious diseases worldwide with a strong impact in developing countries. Mycobacterium tuberculosis, the etiological agent of TB, has a high capacity to evade...
2.
Evidence for the cytotoxic effects of Mycobacterium tuberculosis phospholipase C towards macrophages
Bakala Ngoma J, Schue M, Carriere F, Geerlof A, Canaan S
Biochim Biophys Acta
. 2010 Aug;
1801(12):1305-13.
PMID: 20736081
Phospholipase Cs (PLCs) contribute importantly to the virulence and pathogenicity of several bacteria. It has been reported in previous studies that mutations in the four predicted plc genes of Mycobacterium...
3.
Cotes K, Bakala Ngoma J, Dhouib R, Douchet I, Maurin D, Carriere F, et al.
Appl Microbiol Biotechnol
. 2008 Mar;
78(5):741-9.
PMID: 18309478
Mycobacterium tuberculosis is a bacterial pathogen that can persist for decades in an infected patient without causing a disease. In vivo, the tubercle bacillus present in the lungs store triacylglycerols...
4.
Miled N, Bussetta C, De Caro A, Riviere M, Berti L, Canaan S
Comp Biochem Physiol B Biochem Mol Biol
. 2003 Aug;
136(1):131-8.
PMID: 12941646
Human gastric lipase (HGL) is an enzyme secreted by the stomach, which is stable and active despite the highly acidic environment. It has been clearly established that this enzyme is...
5.
Muthalif M, Hefner Y, Canaan S, Harper J, Zhou H, Parmentier J, et al.
J Biol Chem
. 2001 Aug;
276(43):39653-60.
PMID: 11479288
Calcium-/calmodulin-dependent protein kinase II (CaM kinase II), a decoder of Ca(2+) signals, and cytosolic phospholipase A(2) (cPLA(2)), an enzyme involved in arachidonate release, are involved in many physiological and pathophysiological...
6.
Miled N, Canaan S, Dupuis L, Roussel A, Riviere M, Carriere F, et al.
Biochimie
. 2000 Dec;
82(11):973-86.
PMID: 11099794
Human gastric lipase (HGL) is a lipolytic enzyme that is secreted by the chief cells located in the fundic part of the stomach. HGL plays an important role in lipid...
7.
Canaan S, Roussel A, Verger R, Cambillau C
Biochim Biophys Acta
. 1999 Nov;
1441(2-3):197-204.
PMID: 10570247
Fat digestion in humans requires not only the classical pancreatic lipase but also gastric lipase, which is stable and active despite the highly acidic stomach environment. We have solved the...
8.
Wicker-Planquart C, Canaan S, Riviere M, Dupuis L
Eur J Biochem
. 1999 Jul;
262(3):644-51.
PMID: 10411623
Human gastric lipase (HGL) is a highly glycosylated protein, as glycan chains account for about 15% of the molecular mass of the native HGL. Four potential N-glycosylation consensus sites (Asn15,...
9.
Roussel A, Canaan S, Egloff M, Riviere M, Dupuis L, Verger R, et al.
J Biol Chem
. 1999 Jun;
274(24):16995-7002.
PMID: 10358049
Fat digestion in humans requires not only the classical pancreatic lipase but also gastric lipase, which is stable and active despite the highly acidic stomach environment. We report here the...
10.
Canaan S, Riviere M, Verger R, Dupuis L
Biochem Biophys Res Commun
. 1999 Apr;
257(3):851-4.
PMID: 10208872
Recombinant human gastric lipase (rHGL) and three of its cysteine mutants (cysteine 227, 236, and 244 substitued for threonine or serine) were expressed in the baculovirus/insect cell system and purified...