S A Stacker
Overview
Explore the profile of S A Stacker including associated specialties, affiliations and a list of published articles.
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Articles
59
Citations
3268
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Recent Articles
1.
Malaterre J, Pereira L, Putoczki T, Millen R, Paquet-Fifield S, Germann M, et al.
Oncogene
. 2015 Aug;
35(19):2475-84.
PMID: 26300002
Transcription factor Myb is overexpressed in most colorectal cancers (CRC). Patients with CRC expressing the highest Myb are more likely to relapse. We previously showed that mono-allelic loss of Myb...
2.
Lewin J, Khamly K, Young R, Mitchell C, Hicks R, Toner G, et al.
Br J Cancer
. 2014 Oct;
111(12):2254-61.
PMID: 25321190
Background: Preoperative radiotherapy (RT) is commonly used to treat localised soft-tissue sarcomas (STS). Hypoxia is an important determinant of radioresistance. Whether antiangiogenic therapy can 'normalise' tumour vasculature, thereby improving oxygenation,...
3.
Farnsworth R, Lackmann M, Achen M, Stacker S
Oncogene
. 2013 Aug;
33(27):3496-505.
PMID: 23912450
The growth and dissemination of tumors rely on an altered vascular network, which supports their survival and expansion and provides accessibility to the vasculature and a route of transport for...
4.
Balanathan P, Williams E, Wang H, Pedersen J, Horvath L, Achen M, et al.
Br J Cancer
. 2009 May;
100(11):1784-93.
PMID: 19436293
The biological function of inhibin-alpha subunit (INH alpha) in prostate cancer (PCa) is currently unclear. A recent study associated elevated levels of INH alpha in PCa patients with a higher...
5.
Achen M, Mann G, Stacker S
Br J Cancer
. 2006 Apr;
94(10):1355-60.
PMID: 16641900
Recent studies involving animal models of cancer and clinicopathological analyses of human tumours suggest that the growth of lymphatic vessels (lymphangiogenesis) in or nearby tumours is associated with the metastatic...
6.
Stacker S, Hughes R, Williams R, Achen M
Curr Med Chem
. 2006 Apr;
13(7):783-92.
PMID: 16611067
The recent discovery that members of the vascular endothelial growth factor (VEGF) family of secreted glycoproteins can mediate lymphatic vessel growth (lymphangiogenesis) via cell surface receptor tyrosine kinases expressed on...
7.
Rutanen J, Turunen A, Teittinen M, Rissanen T, Heikura T, Koponen J, et al.
Gene Ther
. 2005 Mar;
12(12):980-7.
PMID: 15759018
Gene transfer to the vessel wall using vascular endothelial growth factors (VEGFs) has shown therapeutic potential for the treatment of restenosis. In this study, we evaluated the effect of catheter-mediated...
8.
Stacker S, Hughes R, Achen M
Curr Pharm Des
. 2004 Feb;
10(1):65-74.
PMID: 14754406
The dysfunction or proliferation of lymphatic vessels (lymphangiogenesis) is linked to a number of pathological conditions including lymphedema and cancer. The recent discovery and characterisation of the lymphangiogenic growth factors...
9.
Debinski W, Slagle-Webb B, Achen M, Stacker S, Tulchinsky E, Gillespie G, et al.
Mol Med
. 2002 Jan;
7(9):598-608.
PMID: 11778649
Background: Glioblastoma multiforme (GBM) is a hypervascularized and locally infiltrating brain tumor of astroglial origin with a very poor prognosis. An X-linked c-fos oncogene-inducible mitogenic, morphogenic, and angiogenic factor, endothelial...
10.
Baldwin M, Roufail S, Halford M, Alitalo K, Stacker S, Achen M
J Biol Chem
. 2001 Sep;
276(47):44307-14.
PMID: 11574540
The secreted glycoprotein vascular endothelial growth factor-D (VEGF-D) is angiogenic, lymphangiogenic, and promotes metastatic spread of tumor cells via lymphatic vessels. VEGF-D consists of a receptor-binding domain (VEGF homology domain)...