Ryoko Okamoto
Overview
Explore the profile of Ryoko Okamoto including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
1050
Followers
0
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Recent Articles
1.
Ahn S, Jain A, Kasuba K, Seimiya M, Okamoto R, Treutlein B, et al.
Biomaterials
. 2024 Apr;
308:122560.
PMID: 38603826
Cells assemble fibronectin, the major extracellular matrix (ECM) protein, into fibrillar matrices, which serve as 3D architectural scaffolds to provide, together with other ECM proteins tissue-specific environments. Although recent approaches...
2.
Auf der Maur P, Trefny M, Baumann Z, Vulin M, Correia A, Diepenbruck M, et al.
Cell Rep Med
. 2023 Apr;
4(4):101002.
PMID: 37044095
A genome-wide PiggyBac transposon-mediated screen and a resistance screen in a PIK3CA-mutated murine tumor model reveal NF1 loss in mammary tumors resistant to the phosphatidylinositol 3-kinase α (PI3Kα)-selective inhibitor alpelisib....
3.
Fleck J, Jansen S, Wollny D, Zenk F, Seimiya M, Jain A, et al.
Nature
. 2022 Oct;
621(7978):365-372.
PMID: 36198796
Self-organizing neural organoids grown from pluripotent stem cells combined with single-cell genomic technologies provide opportunities to examine gene regulatory networks underlying human brain development. Here we acquire single-cell transcriptome and...
4.
Vulin M, Jehanno C, Sethi A, Correia A, Obradovic M, Couto J, et al.
Oncogene
. 2022 Aug;
41(39):4459-4473.
PMID: 36008466
Plasticity delineates cancer subtypes with more or less favourable outcomes. In breast cancer, the subtype triple-negative lacks expression of major differentiation markers, e.g., estrogen receptor α (ERα), and its high...
5.
Correia A, Guimaraes J, Auf der Maur P, De Silva D, Trefny M, Okamoto R, et al.
Nature
. 2021 Nov;
600(7887):E7.
PMID: 34764479
No abstract available.
6.
Correia A, Guimaraes J, Auf der Maur P, De Silva D, Trefny M, Okamoto R, et al.
Nature
. 2021 Jun;
594(7864):566-571.
PMID: 34079127
The persistence of undetectable disseminated tumour cells (DTCs) after primary tumour resection poses a major challenge to effective cancer treatment. These enduring dormant DTCs are seeds of future metastases, and...
7.
Kiriyama Y, Tani A, Kadoya M, Okamoto R, Nochi H
Biol Pharm Bull
. 2020 Mar;
43(6):1020-1022.
PMID: 32201424
Glioblastoma comprises 54% of all the gliomas derived from glial cells and are lethally malignant tumors of the central nervous system (CNS). Glioma cells disrupt the blood-brain barrier, leading to...
8.
Obradovic M, Hamelin B, Manevski N, Couto J, Sethi A, Coissieux M, et al.
Nature
. 2019 Mar;
567(7749):540-544.
PMID: 30867597
Diversity within or between tumours and metastases (known as intra-patient tumour heterogeneity) that develops during disease progression is a serious hurdle for therapy. Metastasis is the fatal hallmark of cancer...
9.
Madan V, Kanojia D, Li J, Okamoto R, Sato-Otsubo A, Kohlmann A, et al.
Nat Commun
. 2015 Jan;
6:6042.
PMID: 25586593
Somatic mutations in the spliceosome gene ZRSR2-located on the X chromosome-are associated with myelodysplastic syndrome (MDS). ZRSR2 is involved in the recognition of 3'-splice site during the early stages of...
10.
Nowak D, Liem N, Mossner M, Klaumunzer M, Papa R, Nowak V, et al.
Exp Hematol
. 2014 Dec;
43(1):32-43.e1-35.
PMID: 25450514
The use of genome-wide copy-number analysis and massive parallel sequencing has revolutionized the understanding of the clonal architecture of pediatric acute lymphoblastic leukemia (ALL) by demonstrating that this disease is...